Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation

Autophagy is known to promote cellular survival upon starvation, although how recycled components fit into cellular metabolism has not been well established. Here, the authors show in yeast that autophagy tunes cellular metabolism based on nitrogen availability via glutamate and aspartate synthesis.

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Autores principales:	Kuanqing Liu, Benjamin M. Sutter, Benjamin P. Tu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7dc0cc2461ad4367ae41ba3d6f44b99a
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spelling	oai:doaj.org-article:7dc0cc2461ad4367ae41ba3d6f44b99a2021-12-02T15:08:00ZAutophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation10.1038/s41467-020-20253-62041-1723https://doaj.org/article/7dc0cc2461ad4367ae41ba3d6f44b99a2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20253-6https://doaj.org/toc/2041-1723Autophagy is known to promote cellular survival upon starvation, although how recycled components fit into cellular metabolism has not been well established. Here, the authors show in yeast that autophagy tunes cellular metabolism based on nitrogen availability via glutamate and aspartate synthesis.Kuanqing LiuBenjamin M. SutterBenjamin P. TuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kuanqing Liu Benjamin M. Sutter Benjamin P. Tu Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation
description	Autophagy is known to promote cellular survival upon starvation, although how recycled components fit into cellular metabolism has not been well established. Here, the authors show in yeast that autophagy tunes cellular metabolism based on nitrogen availability via glutamate and aspartate synthesis.
format	article
author	Kuanqing Liu Benjamin M. Sutter Benjamin P. Tu
author_facet	Kuanqing Liu Benjamin M. Sutter Benjamin P. Tu
author_sort	Kuanqing Liu
title	Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation
title_short	Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation
title_full	Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation
title_fullStr	Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation
title_full_unstemmed	Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation
title_sort	autophagy sustains glutamate and aspartate synthesis in saccharomyces cerevisiae during nitrogen starvation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7dc0cc2461ad4367ae41ba3d6f44b99a
work_keys_str_mv	AT kuanqingliu autophagysustainsglutamateandaspartatesynthesisinsaccharomycescerevisiaeduringnitrogenstarvation AT benjaminmsutter autophagysustainsglutamateandaspartatesynthesisinsaccharomycescerevisiaeduringnitrogenstarvation AT benjaminptu autophagysustainsglutamateandaspartatesynthesisinsaccharomycescerevisiaeduringnitrogenstarvation
_version_	1718388325176311808

Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation

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