Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus
This review addresses clinical picture of acute coronary syndrome (ACS) in patients with type 2 diabetes mellitus (T2DM), the corre- sponding epidemiology data, morphological characteristics and prognosis. ACS in patients with T2DM features fulminant development, and its high lethality is due to chr...
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Endocrinology Research Centre
2013
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oai:doaj.org-article:7dcb73d0d09f4bd383cbb400c3b77b272021-11-14T09:00:18ZClinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus2072-03512072-037810.14341/2072-0351-3754https://doaj.org/article/7dcb73d0d09f4bd383cbb400c3b77b272013-06-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/3754https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378This review addresses clinical picture of acute coronary syndrome (ACS) in patients with type 2 diabetes mellitus (T2DM), the corre- sponding epidemiology data, morphological characteristics and prognosis. ACS in patients with T2DM features fulminant development, and its high lethality is due to chronic ischemic alterations in myocardium (the so-called ?metabolic ischemia?), as well as concomitant microangiopathy. It is more common for patients with T2DM to develop such complications of ACS as cardiogenic shock, acute left ventricular failure and arrhythmia that result in increased lethality during early hours of hospital admission when myocardial necrosis is yet to occur. Percutaneous translumenal intervention is by far the most effective method of ACS management in patients with T2DM. Whenever it is not available, a thrombolytic approach is indicated.Sergey Valentinovich KakorinLev Borisovich KruglyiAshot Musaelovich MkrtumyanEndocrinology Research Centrearticletype 2 diabetes mellitusacute coronary syndromemyocardial infarctionmetabolic ischemiamacroangiopathymicro- angiopathyrevascularizationNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 16, Iss 2, Pp 36-42 (2013) |
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DOAJ |
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DOAJ |
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EN RU |
| topic |
type 2 diabetes mellitus acute coronary syndrome myocardial infarction metabolic ischemia macroangiopathy micro- angiopathy revascularization Nutritional diseases. Deficiency diseases RC620-627 |
| spellingShingle |
type 2 diabetes mellitus acute coronary syndrome myocardial infarction metabolic ischemia macroangiopathy micro- angiopathy revascularization Nutritional diseases. Deficiency diseases RC620-627 Sergey Valentinovich Kakorin Lev Borisovich Kruglyi Ashot Musaelovich Mkrtumyan Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
| description |
This review addresses clinical picture of acute coronary syndrome (ACS) in patients with type 2 diabetes mellitus (T2DM), the corre- sponding epidemiology data, morphological characteristics and prognosis. ACS in patients with T2DM features fulminant development, and its high lethality is due to chronic ischemic alterations in myocardium (the so-called ?metabolic ischemia?), as well as concomitant microangiopathy. It is more common for patients with T2DM to develop such complications of ACS as cardiogenic shock, acute left ventricular failure and arrhythmia that result in increased lethality during early hours of hospital admission when myocardial necrosis is yet to occur. Percutaneous translumenal intervention is by far the most effective method of ACS management in patients with T2DM. Whenever it is not available, a thrombolytic approach is indicated. |
| format |
article |
| author |
Sergey Valentinovich Kakorin Lev Borisovich Kruglyi Ashot Musaelovich Mkrtumyan |
| author_facet |
Sergey Valentinovich Kakorin Lev Borisovich Kruglyi Ashot Musaelovich Mkrtumyan |
| author_sort |
Sergey Valentinovich Kakorin |
| title |
Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
| title_short |
Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
| title_full |
Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
| title_fullStr |
Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
| title_full_unstemmed |
Clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
| title_sort |
clinical and morphological characteristics, management and prognosis for acute coronary syndrome in patients with type 2 diabetes mellitus |
| publisher |
Endocrinology Research Centre |
| publishDate |
2013 |
| url |
https://doaj.org/article/7dcb73d0d09f4bd383cbb400c3b77b27 |
| work_keys_str_mv |
AT sergeyvalentinovichkakorin clinicalandmorphologicalcharacteristicsmanagementandprognosisforacutecoronarysyndromeinpatientswithtype2diabetesmellitus AT levborisovichkruglyi clinicalandmorphologicalcharacteristicsmanagementandprognosisforacutecoronarysyndromeinpatientswithtype2diabetesmellitus AT ashotmusaelovichmkrtumyan clinicalandmorphologicalcharacteristicsmanagementandprognosisforacutecoronarysyndromeinpatientswithtype2diabetesmellitus |
| _version_ |
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