Amnion signals are essential for mesoderm formation in primates

Human and murine embryonic development has disparities, highlighting the need for primate systems. Here, the authors construct a post-implantation transcriptional atlas from non-human primate embryos and show ISL1 controls a gene regulatory network in the amnion required for mesoderm formation.

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Autores principales:	Ran Yang, Alexander Goedel, Yu Kang, Chenyang Si, Chu Chu, Yi Zheng, Zhenzhen Chen, Peter J. Gruber, Yao Xiao, Chikai Zhou, Nevin Witman, Elif Eroglu, Chuen-Yan Leung, Yongchang Chen, Jianping Fu, Weizhi Ji, Fredrik Lanner, Yuyu Niu, Kenneth R. Chien
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7dccdc1bc5d94178bbec12844860f1f9
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spelling	oai:doaj.org-article:7dccdc1bc5d94178bbec12844860f1f92021-12-02T19:02:28ZAmnion signals are essential for mesoderm formation in primates10.1038/s41467-021-25186-22041-1723https://doaj.org/article/7dccdc1bc5d94178bbec12844860f1f92021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25186-2https://doaj.org/toc/2041-1723Human and murine embryonic development has disparities, highlighting the need for primate systems. Here, the authors construct a post-implantation transcriptional atlas from non-human primate embryos and show ISL1 controls a gene regulatory network in the amnion required for mesoderm formation.Ran YangAlexander GoedelYu KangChenyang SiChu ChuYi ZhengZhenzhen ChenPeter J. GruberYao XiaoChikai ZhouNevin WitmanElif ErogluChuen-Yan LeungYongchang ChenJianping FuWeizhi JiFredrik LannerYuyu NiuKenneth R. ChienNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ran Yang Alexander Goedel Yu Kang Chenyang Si Chu Chu Yi Zheng Zhenzhen Chen Peter J. Gruber Yao Xiao Chikai Zhou Nevin Witman Elif Eroglu Chuen-Yan Leung Yongchang Chen Jianping Fu Weizhi Ji Fredrik Lanner Yuyu Niu Kenneth R. Chien Amnion signals are essential for mesoderm formation in primates
description	Human and murine embryonic development has disparities, highlighting the need for primate systems. Here, the authors construct a post-implantation transcriptional atlas from non-human primate embryos and show ISL1 controls a gene regulatory network in the amnion required for mesoderm formation.
format	article
author	Ran Yang Alexander Goedel Yu Kang Chenyang Si Chu Chu Yi Zheng Zhenzhen Chen Peter J. Gruber Yao Xiao Chikai Zhou Nevin Witman Elif Eroglu Chuen-Yan Leung Yongchang Chen Jianping Fu Weizhi Ji Fredrik Lanner Yuyu Niu Kenneth R. Chien
author_facet	Ran Yang Alexander Goedel Yu Kang Chenyang Si Chu Chu Yi Zheng Zhenzhen Chen Peter J. Gruber Yao Xiao Chikai Zhou Nevin Witman Elif Eroglu Chuen-Yan Leung Yongchang Chen Jianping Fu Weizhi Ji Fredrik Lanner Yuyu Niu Kenneth R. Chien
author_sort	Ran Yang
title	Amnion signals are essential for mesoderm formation in primates
title_short	Amnion signals are essential for mesoderm formation in primates
title_full	Amnion signals are essential for mesoderm formation in primates
title_fullStr	Amnion signals are essential for mesoderm formation in primates
title_full_unstemmed	Amnion signals are essential for mesoderm formation in primates
title_sort	amnion signals are essential for mesoderm formation in primates
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7dccdc1bc5d94178bbec12844860f1f9
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Amnion signals are essential for mesoderm formation in primates

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