Safety study of malapposition of the bio-corrodible nitrided iron stent in vivo
To evaluate the safety of stent malapposition of corrodible nitride iron stent as biodegradable cardiovascular implants, a total of 108 stents were implanted into the abdominal aortas, iliac arteries, and iliac artery bifurcations of 36 New Zealand white rabbits separately. Each rabbit was implanted...
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De Gruyter
2021
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oai:doaj.org-article:7dd49fc16d0248d0a8b4efd0a41000e92021-12-05T14:10:58ZSafety study of malapposition of the bio-corrodible nitrided iron stent in vivo2191-909710.1515/ntrev-2021-0062https://doaj.org/article/7dd49fc16d0248d0a8b4efd0a41000e92021-08-01T00:00:00Zhttps://doi.org/10.1515/ntrev-2021-0062https://doaj.org/toc/2191-9097To evaluate the safety of stent malapposition of corrodible nitride iron stent as biodegradable cardiovascular implants, a total of 108 stents were implanted into the abdominal aortas, iliac arteries, and iliac artery bifurcations of 36 New Zealand white rabbits separately. Each rabbit was implanted with three stents. After a follow-up period of 3 months, no thrombus and embolism were found in local and downstream vessels. And no other adverse events occurred either. Stent strut covered by endothelial layer started to show signs of degradation, while struts exposed to bifurcated blood flow covered by a layer of tissue and no rust particle was found on the surface. Also, there were no traces of thrombosis and traces of excess inflammation. The authors conclude that the risk brought by stent malapposition in less than 9 months is acceptable.Shi XiaoliWang JinZhang GuiZhang LuZhang WanqianCao PingWang GeqiZhang DeyuanQin LiDe Gruyterarticlebio-absorb iron stentcorrosioniron overloadstent malappositionthrombosisTechnologyTChemical technologyTP1-1185Physical and theoretical chemistryQD450-801ENNanotechnology Reviews, Vol 10, Iss 1, Pp 839-846 (2021) |
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bio-absorb iron stent corrosion iron overload stent malapposition thrombosis Technology T Chemical technology TP1-1185 Physical and theoretical chemistry QD450-801 |
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bio-absorb iron stent corrosion iron overload stent malapposition thrombosis Technology T Chemical technology TP1-1185 Physical and theoretical chemistry QD450-801 Shi Xiaoli Wang Jin Zhang Gui Zhang Lu Zhang Wanqian Cao Ping Wang Geqi Zhang Deyuan Qin Li Safety study of malapposition of the bio-corrodible nitrided iron stent in vivo |
description |
To evaluate the safety of stent malapposition of corrodible nitride iron stent as biodegradable cardiovascular implants, a total of 108 stents were implanted into the abdominal aortas, iliac arteries, and iliac artery bifurcations of 36 New Zealand white rabbits separately. Each rabbit was implanted with three stents. After a follow-up period of 3 months, no thrombus and embolism were found in local and downstream vessels. And no other adverse events occurred either. Stent strut covered by endothelial layer started to show signs of degradation, while struts exposed to bifurcated blood flow covered by a layer of tissue and no rust particle was found on the surface. Also, there were no traces of thrombosis and traces of excess inflammation. The authors conclude that the risk brought by stent malapposition in less than 9 months is acceptable. |
format |
article |
author |
Shi Xiaoli Wang Jin Zhang Gui Zhang Lu Zhang Wanqian Cao Ping Wang Geqi Zhang Deyuan Qin Li |
author_facet |
Shi Xiaoli Wang Jin Zhang Gui Zhang Lu Zhang Wanqian Cao Ping Wang Geqi Zhang Deyuan Qin Li |
author_sort |
Shi Xiaoli |
title |
Safety study of malapposition of the bio-corrodible nitrided iron stent in vivo |
title_short |
Safety study of malapposition of the bio-corrodible nitrided iron stent in vivo |
title_full |
Safety study of malapposition of the bio-corrodible nitrided iron stent in vivo |
title_fullStr |
Safety study of malapposition of the bio-corrodible nitrided iron stent in vivo |
title_full_unstemmed |
Safety study of malapposition of the bio-corrodible nitrided iron stent in vivo |
title_sort |
safety study of malapposition of the bio-corrodible nitrided iron stent in vivo |
publisher |
De Gruyter |
publishDate |
2021 |
url |
https://doaj.org/article/7dd49fc16d0248d0a8b4efd0a41000e9 |
work_keys_str_mv |
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