Hexosamine biosynthetic pathway and O-GlcNAc-processing enzymes regulate daily rhythms in protein O-GlcNAcylation
Misalignment between lifestyle and the natural day-night cycle, such as mistimed eating, can negatively impact health. Here the authors show that mistimed feeding alters protein O-GlcNAcylation, a nutrient sensitive post-translational modification.
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Nature Portfolio
2021
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oai:doaj.org-article:7dd753e5c95d4a248376025b6e7680332021-12-02T15:39:43ZHexosamine biosynthetic pathway and O-GlcNAc-processing enzymes regulate daily rhythms in protein O-GlcNAcylation10.1038/s41467-021-24301-72041-1723https://doaj.org/article/7dd753e5c95d4a248376025b6e7680332021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24301-7https://doaj.org/toc/2041-1723Misalignment between lifestyle and the natural day-night cycle, such as mistimed eating, can negatively impact health. Here the authors show that mistimed feeding alters protein O-GlcNAcylation, a nutrient sensitive post-translational modification.Xianhui LiuIvana BlaženovićAdam J. ContrerasThu M. PhamChristine A. TabulocYing H. LiJian JiOliver FiehnJoanna C. ChiuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
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Science Q Xianhui Liu Ivana Blaženović Adam J. Contreras Thu M. Pham Christine A. Tabuloc Ying H. Li Jian Ji Oliver Fiehn Joanna C. Chiu Hexosamine biosynthetic pathway and O-GlcNAc-processing enzymes regulate daily rhythms in protein O-GlcNAcylation |
description |
Misalignment between lifestyle and the natural day-night cycle, such as mistimed eating, can negatively impact health. Here the authors show that mistimed feeding alters protein O-GlcNAcylation, a nutrient sensitive post-translational modification. |
format |
article |
author |
Xianhui Liu Ivana Blaženović Adam J. Contreras Thu M. Pham Christine A. Tabuloc Ying H. Li Jian Ji Oliver Fiehn Joanna C. Chiu |
author_facet |
Xianhui Liu Ivana Blaženović Adam J. Contreras Thu M. Pham Christine A. Tabuloc Ying H. Li Jian Ji Oliver Fiehn Joanna C. Chiu |
author_sort |
Xianhui Liu |
title |
Hexosamine biosynthetic pathway and O-GlcNAc-processing enzymes regulate daily rhythms in protein O-GlcNAcylation |
title_short |
Hexosamine biosynthetic pathway and O-GlcNAc-processing enzymes regulate daily rhythms in protein O-GlcNAcylation |
title_full |
Hexosamine biosynthetic pathway and O-GlcNAc-processing enzymes regulate daily rhythms in protein O-GlcNAcylation |
title_fullStr |
Hexosamine biosynthetic pathway and O-GlcNAc-processing enzymes regulate daily rhythms in protein O-GlcNAcylation |
title_full_unstemmed |
Hexosamine biosynthetic pathway and O-GlcNAc-processing enzymes regulate daily rhythms in protein O-GlcNAcylation |
title_sort |
hexosamine biosynthetic pathway and o-glcnac-processing enzymes regulate daily rhythms in protein o-glcnacylation |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/7dd753e5c95d4a248376025b6e768033 |
work_keys_str_mv |
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1718385883201142784 |