Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis

Estimated glomerular filtration rate (eGFR) is a measure of kidney function and used to characterize chronic kidney disease. Here, Graham et al. identify 53 novel loci for eGFR in a GWAS meta-analysis, a subset of which are associated with other common diseases, such as diabetes and hypertension, ba...

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Autores principales:	Sarah E. Graham, Jonas B. Nielsen, Matthew Zawistowski, Wei Zhou, Lars G. Fritsche, Maiken E. Gabrielsen, Anne Heidi Skogholt, Ida Surakka, Whitney E. Hornsby, Damian Fermin, Daniel B. Larach, Sachin Kheterpal, Chad M. Brummett, Seunggeun Lee, Hyun Min Kang, Goncalo R. Abecasis, Solfrid Romundstad, Stein Hallan, Matthew G. Sampson, Kristian Hveem, Cristen J. Willer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7de7f4e3a4e84b4f97be7b7ad13ccb61
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spelling	oai:doaj.org-article:7de7f4e3a4e84b4f97be7b7ad13ccb612021-12-02T17:01:51ZSex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis10.1038/s41467-019-09861-z2041-1723https://doaj.org/article/7de7f4e3a4e84b4f97be7b7ad13ccb612019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09861-zhttps://doaj.org/toc/2041-1723Estimated glomerular filtration rate (eGFR) is a measure of kidney function and used to characterize chronic kidney disease. Here, Graham et al. identify 53 novel loci for eGFR in a GWAS meta-analysis, a subset of which are associated with other common diseases, such as diabetes and hypertension, based on PheWAS.Sarah E. GrahamJonas B. NielsenMatthew ZawistowskiWei ZhouLars G. FritscheMaiken E. GabrielsenAnne Heidi SkogholtIda SurakkaWhitney E. HornsbyDamian FerminDaniel B. LarachSachin KheterpalChad M. BrummettSeunggeun LeeHyun Min KangGoncalo R. AbecasisSolfrid RomundstadStein HallanMatthew G. SampsonKristian HveemCristen J. WillerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sarah E. Graham Jonas B. Nielsen Matthew Zawistowski Wei Zhou Lars G. Fritsche Maiken E. Gabrielsen Anne Heidi Skogholt Ida Surakka Whitney E. Hornsby Damian Fermin Daniel B. Larach Sachin Kheterpal Chad M. Brummett Seunggeun Lee Hyun Min Kang Goncalo R. Abecasis Solfrid Romundstad Stein Hallan Matthew G. Sampson Kristian Hveem Cristen J. Willer Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis
description	Estimated glomerular filtration rate (eGFR) is a measure of kidney function and used to characterize chronic kidney disease. Here, Graham et al. identify 53 novel loci for eGFR in a GWAS meta-analysis, a subset of which are associated with other common diseases, such as diabetes and hypertension, based on PheWAS.
format	article
author	Sarah E. Graham Jonas B. Nielsen Matthew Zawistowski Wei Zhou Lars G. Fritsche Maiken E. Gabrielsen Anne Heidi Skogholt Ida Surakka Whitney E. Hornsby Damian Fermin Daniel B. Larach Sachin Kheterpal Chad M. Brummett Seunggeun Lee Hyun Min Kang Goncalo R. Abecasis Solfrid Romundstad Stein Hallan Matthew G. Sampson Kristian Hveem Cristen J. Willer
author_facet	Sarah E. Graham Jonas B. Nielsen Matthew Zawistowski Wei Zhou Lars G. Fritsche Maiken E. Gabrielsen Anne Heidi Skogholt Ida Surakka Whitney E. Hornsby Damian Fermin Daniel B. Larach Sachin Kheterpal Chad M. Brummett Seunggeun Lee Hyun Min Kang Goncalo R. Abecasis Solfrid Romundstad Stein Hallan Matthew G. Sampson Kristian Hveem Cristen J. Willer
author_sort	Sarah E. Graham
title	Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis
title_short	Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis
title_full	Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis
title_fullStr	Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis
title_full_unstemmed	Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis
title_sort	sex-specific and pleiotropic effects underlying kidney function identified from gwas meta-analysis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/7de7f4e3a4e84b4f97be7b7ad13ccb61
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Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis

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