Optimisation of prime-boost immunization in mice using novel protein-based and recombinant vaccinia (Tiantan)-based HBV vaccine.

<h4>Background</h4>A therapeutic vaccine for chronic hepatitis B virus (HBV) infection that enhances virus-specific cellular immune responses is urgently needed. The "prime-boost" regimen is a widely used vaccine strategy against many persistence infections. However, few report...

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Autores principales: Hong Chen, Xia Chuai, Yao Deng, Bo Wen, Wen Wang, Shaoqing Xiong, Li Ruan, Wenjie Tan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/7df43b65b6dd4569ab70422fdcfff997
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