Caloric restriction delays age-related methylation drift

Caloric restriction has been shown to increase lifespan in mammals. Here, the authors provide evidence that age-related methylation drift correlates with lifespan and that caloric restriction in mice and rhesus monkeys results in attenuation of age-related methylation drift.

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Autores principales:	Shinji Maegawa, Yue Lu, Tomomitsu Tahara, Justin T. Lee, Jozef Madzo, Shoudan Liang, Jaroslav Jelinek, Ricki J. Colman, Jean-Pierre J. Issa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7df8716f28e94df0a4d186d22d31c1a2
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spelling	oai:doaj.org-article:7df8716f28e94df0a4d186d22d31c1a22021-12-02T17:06:09ZCaloric restriction delays age-related methylation drift10.1038/s41467-017-00607-32041-1723https://doaj.org/article/7df8716f28e94df0a4d186d22d31c1a22017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00607-3https://doaj.org/toc/2041-1723Caloric restriction has been shown to increase lifespan in mammals. Here, the authors provide evidence that age-related methylation drift correlates with lifespan and that caloric restriction in mice and rhesus monkeys results in attenuation of age-related methylation drift.Shinji MaegawaYue LuTomomitsu TaharaJustin T. LeeJozef MadzoShoudan LiangJaroslav JelinekRicki J. ColmanJean-Pierre J. IssaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shinji Maegawa Yue Lu Tomomitsu Tahara Justin T. Lee Jozef Madzo Shoudan Liang Jaroslav Jelinek Ricki J. Colman Jean-Pierre J. Issa Caloric restriction delays age-related methylation drift
description	Caloric restriction has been shown to increase lifespan in mammals. Here, the authors provide evidence that age-related methylation drift correlates with lifespan and that caloric restriction in mice and rhesus monkeys results in attenuation of age-related methylation drift.
format	article
author	Shinji Maegawa Yue Lu Tomomitsu Tahara Justin T. Lee Jozef Madzo Shoudan Liang Jaroslav Jelinek Ricki J. Colman Jean-Pierre J. Issa
author_facet	Shinji Maegawa Yue Lu Tomomitsu Tahara Justin T. Lee Jozef Madzo Shoudan Liang Jaroslav Jelinek Ricki J. Colman Jean-Pierre J. Issa
author_sort	Shinji Maegawa
title	Caloric restriction delays age-related methylation drift
title_short	Caloric restriction delays age-related methylation drift
title_full	Caloric restriction delays age-related methylation drift
title_fullStr	Caloric restriction delays age-related methylation drift
title_full_unstemmed	Caloric restriction delays age-related methylation drift
title_sort	caloric restriction delays age-related methylation drift
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/7df8716f28e94df0a4d186d22d31c1a2
work_keys_str_mv	AT shinjimaegawa caloricrestrictiondelaysagerelatedmethylationdrift AT yuelu caloricrestrictiondelaysagerelatedmethylationdrift AT tomomitsutahara caloricrestrictiondelaysagerelatedmethylationdrift AT justintlee caloricrestrictiondelaysagerelatedmethylationdrift AT jozefmadzo caloricrestrictiondelaysagerelatedmethylationdrift AT shoudanliang caloricrestrictiondelaysagerelatedmethylationdrift AT jaroslavjelinek caloricrestrictiondelaysagerelatedmethylationdrift AT rickijcolman caloricrestrictiondelaysagerelatedmethylationdrift AT jeanpierrejissa caloricrestrictiondelaysagerelatedmethylationdrift
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Caloric restriction delays age-related methylation drift

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