Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study

Abstract Background Platelet-rich plasma (PRP) is widely used in the management of lateral elbow tendinopathy (LET) despite conflicting evidence on its effectiveness. With high levels of user experience, this study aimed to assess consensus amongst experts on its clinical use. Methods A three-round...

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Autores principales:	Jonathan P. Evans, Nicola Maffulli, Chris Smith, Adam Watts, Jose Valderas, Vicki Goodwin
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	Platelet-rich plasma PRP Consensus Elbow Tendinopathy Tennis elbow Orthopedic surgery RD701-811
Acceso en línea:	https://doaj.org/article/7e08819dfaa44394908f539e01ecf166
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spelling	oai:doaj.org-article:7e08819dfaa44394908f539e01ecf1662021-11-28T12:30:44ZEven experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study10.1186/s10195-021-00608-51590-99211590-9999https://doaj.org/article/7e08819dfaa44394908f539e01ecf1662021-11-01T00:00:00Zhttps://doi.org/10.1186/s10195-021-00608-5https://doaj.org/toc/1590-9921https://doaj.org/toc/1590-9999Abstract Background Platelet-rich plasma (PRP) is widely used in the management of lateral elbow tendinopathy (LET) despite conflicting evidence on its effectiveness. With high levels of user experience, this study aimed to assess consensus amongst experts on its clinical use. Methods A three-round international Delphi study was conducted. Participants were invited through national society mailing lists and contact lists derived from a systematic search of the literature on PRP. In round one, a primary working group developed 40 statements on PRP preparation and clinical application. In rounds two and three, an international group of researchers on PRP and clinical users of the device scored their levels of agreement with the statements on a five-point scale. Consensus was defined as an interquartile range of ≤ 1. Results Consensus of agreement was only reached for 17/40 (42.5%) statements. For statements on PRP formulation, consensus of agreement was reached in 2/6 statements (33%). Only limited consensus on the contraindications, delivery strategy and delivery technique was achieved. Conclusion Experts reached very limited consensus on the use of PRP in LET. High levels of user experience have not resulted in a convergence of opinion on the technical components of PRP formulation and delivery, substantiating the need for further studies and improved trial reporting.Jonathan P. EvansNicola MaffulliChris SmithAdam WattsJose ValderasVicki GoodwinSpringerOpenarticlePlatelet-rich plasmaPRPConsensusElbowTendinopathyTennis elbowOrthopedic surgeryRD701-811ENJournal of Orthopaedics and Traumatology, Vol 22, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Platelet-rich plasma PRP Consensus Elbow Tendinopathy Tennis elbow Orthopedic surgery RD701-811
spellingShingle	Platelet-rich plasma PRP Consensus Elbow Tendinopathy Tennis elbow Orthopedic surgery RD701-811 Jonathan P. Evans Nicola Maffulli Chris Smith Adam Watts Jose Valderas Vicki Goodwin Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study
description	Abstract Background Platelet-rich plasma (PRP) is widely used in the management of lateral elbow tendinopathy (LET) despite conflicting evidence on its effectiveness. With high levels of user experience, this study aimed to assess consensus amongst experts on its clinical use. Methods A three-round international Delphi study was conducted. Participants were invited through national society mailing lists and contact lists derived from a systematic search of the literature on PRP. In round one, a primary working group developed 40 statements on PRP preparation and clinical application. In rounds two and three, an international group of researchers on PRP and clinical users of the device scored their levels of agreement with the statements on a five-point scale. Consensus was defined as an interquartile range of ≤ 1. Results Consensus of agreement was only reached for 17/40 (42.5%) statements. For statements on PRP formulation, consensus of agreement was reached in 2/6 statements (33%). Only limited consensus on the contraindications, delivery strategy and delivery technique was achieved. Conclusion Experts reached very limited consensus on the use of PRP in LET. High levels of user experience have not resulted in a convergence of opinion on the technical components of PRP formulation and delivery, substantiating the need for further studies and improved trial reporting.
format	article
author	Jonathan P. Evans Nicola Maffulli Chris Smith Adam Watts Jose Valderas Vicki Goodwin
author_facet	Jonathan P. Evans Nicola Maffulli Chris Smith Adam Watts Jose Valderas Vicki Goodwin
author_sort	Jonathan P. Evans
title	Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study
title_short	Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study
title_full	Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study
title_fullStr	Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study
title_full_unstemmed	Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study
title_sort	even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international delphi study
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/7e08819dfaa44394908f539e01ecf166
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Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study

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