Modern antihyperglycemic therapy: safety and efficacy of glimepiride

Current review analyzes pharmacological and clinical aspects of glimepiride from perspective of the evidence-based medicine. We aimedto determine position of glimepiride within modern antihyperglycemic dialectics of safety and efficacy. We also address cardioprotectiveproperties of glimeperide due t...

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Autores principales: Lyudmila Alexandrovna Ruyatkina, Maksim Yur'evich Sorokin
Formato: article
Lenguaje:EN
RU
Publicado: Endocrinology Research Centre 2012
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Acceso en línea:https://doaj.org/article/7e0a54b9cd51417cbf3ed787ad5c41a0
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Sumario:Current review analyzes pharmacological and clinical aspects of glimepiride from perspective of the evidence-based medicine. We aimedto determine position of glimepiride within modern antihyperglycemic dialectics of safety and efficacy. We also address cardioprotectiveproperties of glimeperide due to its anti-atherogenic activity, capacity to correct endothelial dysfunction and hemostatic system, as wellas absence of inhibitory effect on ischemic preconditioning.