Managing Contamination and Diverse Bacterial Loads in 16S rRNA Deep Sequencing of Clinical Samples: Implications of the Law of Small Numbers

Managing Contamination and Diverse Bacterial Loads in 16S rRNA Deep Sequencing of Clinical Samples: Implications of the Law of Small Numbers

There has been a gradual increase in 16S deep sequencing studies on infectious disease materials. Management of bacterial DNA contamination is a major challenge in such diagnostics, particularly in low biomass samples.

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Autores principales: Ruben Dyrhovden, Martin Rippin, Kjell Kåre Øvrebø, Randi M. Nygaard, Elling Ulvestad, Øyvind Kommedal
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/7e158acfaad245d589d8e7bb2c45acab
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