Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study

Shingo Hosoda, Kenya Yuki, Takeshi Ono, Kazuo TsubotaDepartment of Ophthalmology, Keio University School of Medicine, Shinjuku-ku, Tokyo, JapanPurpose: Flat anterior chamber (FAC) in association with overfiltration is a complication after trabeculectomy. The aim of the current study was to investiga...

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Autores principales:	Hosoda S, Yuki K, Ono T, Tsubota K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/7e176f86ab6e470db03409cd147ca272
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spelling	oai:doaj.org-article:7e176f86ab6e470db03409cd147ca2722021-12-02T00:41:50ZOphthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study1177-54671177-5483https://doaj.org/article/7e176f86ab6e470db03409cd147ca2722013-09-01T00:00:00Zhttp://www.dovepress.com/ophthalmic-viscoelastic-device-injection-for-the-treatment-of-flat-ant-a14284https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Shingo Hosoda, Kenya Yuki, Takeshi Ono, Kazuo TsubotaDepartment of Ophthalmology, Keio University School of Medicine, Shinjuku-ku, Tokyo, JapanPurpose: Flat anterior chamber (FAC) in association with overfiltration is a complication after trabeculectomy. The aim of the current study was to investigate the efficacy of injection of an ophthalmic viscoelastic device (OVD) to treat FAC after trabeculectomy in a retrospective consecutive case series study.Materials and methods: Twenty-five consecutive patients who underwent injection of OVD for the treatment of FAC after trabeculectomy were analyzed. The primary outcome variable was the qualified success of trabeculectomy, which was defined at three different levels by the achievement of one of three IOP-related criteria with or without glaucoma medication. Kaplan–Meier plots were generated to estimate survival functions for trabeculectomy with OVD injection.Results: Twenty-one patients (21/25 = 84.0%) recovered from FAC by one OVD injection. The postoperative intraocular pressure (IOP) measured at 12 months, 24 months, 36 months, 48 months, and 60 months was 14.7 ± 3.6 mmHg, 15.6 ± 7.0 mmHg, 14.2 ± 2.8 mmHg, 14.2 ± 3.8 mmHg, and 14.6 ± 2.7 mmHg, respectively. All postoperative IOP measurements were significantly lower than the preoperative IOP (P < 0.001). The probabilities of qualified success for 5 years after trabeculectomy with OVD injection were as follows: 24.4% (IOP ≦ 21 mmHg and ≧20% reduction of preoperative IOP), 16.5% (IOP ≦ 16 mmHg and ≧20% reduction) and 6.3% (IOP ≦ 12 mmHg and ≧30% reduction). One patient, who had undergone deep lamellar keratoplasty, experienced a complication associated with the injection of the viscoelastic material, Descemet's membrane detachment.Conclusion: Injection of OVD may be effective for the treatment of FAC; however, the long-term success rate was relatively low.Keywords: glaucoma, trabeculectomy, flat anterior chamber, ophthalmic viscoelastic device injectionHosoda SYuki KOno TTsubota KDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 1781-1785 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Hosoda S Yuki K Ono T Tsubota K Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
description	Shingo Hosoda, Kenya Yuki, Takeshi Ono, Kazuo TsubotaDepartment of Ophthalmology, Keio University School of Medicine, Shinjuku-ku, Tokyo, JapanPurpose: Flat anterior chamber (FAC) in association with overfiltration is a complication after trabeculectomy. The aim of the current study was to investigate the efficacy of injection of an ophthalmic viscoelastic device (OVD) to treat FAC after trabeculectomy in a retrospective consecutive case series study.Materials and methods: Twenty-five consecutive patients who underwent injection of OVD for the treatment of FAC after trabeculectomy were analyzed. The primary outcome variable was the qualified success of trabeculectomy, which was defined at three different levels by the achievement of one of three IOP-related criteria with or without glaucoma medication. Kaplan–Meier plots were generated to estimate survival functions for trabeculectomy with OVD injection.Results: Twenty-one patients (21/25 = 84.0%) recovered from FAC by one OVD injection. The postoperative intraocular pressure (IOP) measured at 12 months, 24 months, 36 months, 48 months, and 60 months was 14.7 ± 3.6 mmHg, 15.6 ± 7.0 mmHg, 14.2 ± 2.8 mmHg, 14.2 ± 3.8 mmHg, and 14.6 ± 2.7 mmHg, respectively. All postoperative IOP measurements were significantly lower than the preoperative IOP (P < 0.001). The probabilities of qualified success for 5 years after trabeculectomy with OVD injection were as follows: 24.4% (IOP ≦ 21 mmHg and ≧20% reduction of preoperative IOP), 16.5% (IOP ≦ 16 mmHg and ≧20% reduction) and 6.3% (IOP ≦ 12 mmHg and ≧30% reduction). One patient, who had undergone deep lamellar keratoplasty, experienced a complication associated with the injection of the viscoelastic material, Descemet's membrane detachment.Conclusion: Injection of OVD may be effective for the treatment of FAC; however, the long-term success rate was relatively low.Keywords: glaucoma, trabeculectomy, flat anterior chamber, ophthalmic viscoelastic device injection
format	article
author	Hosoda S Yuki K Ono T Tsubota K
author_facet	Hosoda S Yuki K Ono T Tsubota K
author_sort	Hosoda S
title	Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
title_short	Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
title_full	Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
title_fullStr	Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
title_full_unstemmed	Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
title_sort	ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/7e176f86ab6e470db03409cd147ca272
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_version_	1718403564110348288

Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study

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