Analysis of Dot/Icm Type IVB Secretion System Subassemblies by Cryoelectron Tomography Reveals Conformational Changes Induced by DotB Binding

ABSTRACT Type IV secretion systems (T4SSs) are sophisticated nanomachines used by many bacterial pathogens to translocate protein and DNA substrates across a host cell membrane. Although T4SSs have important roles in promoting bacterial infections, little is known about the biogenesis of the apparat...

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Auteurs principaux: Donghyun Park, David Chetrit, Bo Hu, Craig R. Roy, Jun Liu
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
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Accès en ligne:https://doaj.org/article/7e1bcf1f2afc42b7b966cb330d2a0118
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