Gut immunity in a protochordate involves a secreted immunoglobulin-type mediator binding host chitin and bacteria
Protochordates, including Ciona intestinalis, lack an adaptive immune system but possess innate immune receptors, including the secreted immunoglobulin V-region-containing VCBPs. Here the authors show that VCBP-C of Cionabinds gut bacteria and chitin-rich gut mucosa, influences biofilm formation and...
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| Autores principales: | , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/7e1d848d9d37487ca67bad82f4ee9607 |
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| Sumario: | Protochordates, including Ciona intestinalis, lack an adaptive immune system but possess innate immune receptors, including the secreted immunoglobulin V-region-containing VCBPs. Here the authors show that VCBP-C of Cionabinds gut bacteria and chitin-rich gut mucosa, influences biofilm formation and likely plays a role in gut homeostasis. |
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