Dialysis adequacy predictions using a machine learning method

Abstract Dialysis adequacy is an important survival indicator in patients with chronic hemodialysis. However, there are inconveniences and disadvantages to measuring dialysis adequacy by blood samples. This study used machine learning models to predict dialysis adequacy in chronic hemodialysis patie...

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Autores principales: Hyung Woo Kim, Seok-Jae Heo, Jae Young Kim, Annie Kim, Chung-Mo Nam, Beom Seok Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7e25d2b59aef40c79b19d54c65c0fef6
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spelling oai:doaj.org-article:7e25d2b59aef40c79b19d54c65c0fef62021-12-02T16:31:03ZDialysis adequacy predictions using a machine learning method10.1038/s41598-021-94964-12045-2322https://doaj.org/article/7e25d2b59aef40c79b19d54c65c0fef62021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-94964-1https://doaj.org/toc/2045-2322Abstract Dialysis adequacy is an important survival indicator in patients with chronic hemodialysis. However, there are inconveniences and disadvantages to measuring dialysis adequacy by blood samples. This study used machine learning models to predict dialysis adequacy in chronic hemodialysis patients using repeatedly measured data during hemodialysis. This study included 1333 hemodialysis sessions corresponding to the monthly examination dates of 61 patients. Patient demographics and clinical parameters were continuously measured from the hemodialysis machine; 240 measurements were collected from each hemodialysis session. Machine learning models (random forest and extreme gradient boosting [XGBoost]) and deep learning models (convolutional neural network and gated recurrent unit) were compared with multivariable linear regression models. The mean absolute percentage error (MAPE), root mean square error (RMSE), and Spearman’s rank correlation coefficient (Corr) for each model using fivefold cross-validation were calculated as performance measurements. The XGBoost model had the best performance among all methods (MAPE = 2.500; RMSE = 2.906; Corr = 0.873). The deep learning models with convolutional neural network (MAPE = 2.835; RMSE = 3.125; Corr = 0.833) and gated recurrent unit (MAPE = 2.974; RMSE = 3.230; Corr = 0.824) had similar performances. The linear regression models had the lowest performance (MAPE = 3.284; RMSE = 3.586; Corr = 0.770) compared with other models. Machine learning methods can accurately infer hemodialysis adequacy using continuously measured data from hemodialysis machines.Hyung Woo KimSeok-Jae HeoJae Young KimAnnie KimChung-Mo NamBeom Seok KimNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Hyung Woo Kim
Seok-Jae Heo
Jae Young Kim
Annie Kim
Chung-Mo Nam
Beom Seok Kim
Dialysis adequacy predictions using a machine learning method
description Abstract Dialysis adequacy is an important survival indicator in patients with chronic hemodialysis. However, there are inconveniences and disadvantages to measuring dialysis adequacy by blood samples. This study used machine learning models to predict dialysis adequacy in chronic hemodialysis patients using repeatedly measured data during hemodialysis. This study included 1333 hemodialysis sessions corresponding to the monthly examination dates of 61 patients. Patient demographics and clinical parameters were continuously measured from the hemodialysis machine; 240 measurements were collected from each hemodialysis session. Machine learning models (random forest and extreme gradient boosting [XGBoost]) and deep learning models (convolutional neural network and gated recurrent unit) were compared with multivariable linear regression models. The mean absolute percentage error (MAPE), root mean square error (RMSE), and Spearman’s rank correlation coefficient (Corr) for each model using fivefold cross-validation were calculated as performance measurements. The XGBoost model had the best performance among all methods (MAPE = 2.500; RMSE = 2.906; Corr = 0.873). The deep learning models with convolutional neural network (MAPE = 2.835; RMSE = 3.125; Corr = 0.833) and gated recurrent unit (MAPE = 2.974; RMSE = 3.230; Corr = 0.824) had similar performances. The linear regression models had the lowest performance (MAPE = 3.284; RMSE = 3.586; Corr = 0.770) compared with other models. Machine learning methods can accurately infer hemodialysis adequacy using continuously measured data from hemodialysis machines.
format article
author Hyung Woo Kim
Seok-Jae Heo
Jae Young Kim
Annie Kim
Chung-Mo Nam
Beom Seok Kim
author_facet Hyung Woo Kim
Seok-Jae Heo
Jae Young Kim
Annie Kim
Chung-Mo Nam
Beom Seok Kim
author_sort Hyung Woo Kim
title Dialysis adequacy predictions using a machine learning method
title_short Dialysis adequacy predictions using a machine learning method
title_full Dialysis adequacy predictions using a machine learning method
title_fullStr Dialysis adequacy predictions using a machine learning method
title_full_unstemmed Dialysis adequacy predictions using a machine learning method
title_sort dialysis adequacy predictions using a machine learning method
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/7e25d2b59aef40c79b19d54c65c0fef6
work_keys_str_mv AT hyungwookim dialysisadequacypredictionsusingamachinelearningmethod
AT seokjaeheo dialysisadequacypredictionsusingamachinelearningmethod
AT jaeyoungkim dialysisadequacypredictionsusingamachinelearningmethod
AT anniekim dialysisadequacypredictionsusingamachinelearningmethod
AT chungmonam dialysisadequacypredictionsusingamachinelearningmethod
AT beomseokkim dialysisadequacypredictionsusingamachinelearningmethod
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