EPEC Recruits a Cdc42-Specific GEF, Frabin, To Facilitate PAK Activation and Host Cell Colonization
ABSTRACT Enteropathogenic Escherichia coli (EPEC) is an extracellular pathogen that tightly adheres to host cells by forming “actin pedestals” beneath the bacteria, a critical step in pathogenesis. EPEC injects effector proteins that manipulate host cell signaling cascades to trigger pedestal assemb...
Guardado en:
Autores principales: | Vikash Singh, Peter J. Hume, Anthony Davidson, Vassilis Koronakis |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7e27a2ed99ff406f9ea742c2ce9ed96f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Pathogenic <named-content content-type="genus-species">Escherichia coli</named-content> Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation
por: Vikash Singh, et al.
Publicado: (2019) -
A kinase-independent function of PAK is crucial for pathogen-mediated actin remodelling.
por: Anthony Davidson, et al.
Publicado: (2021) -
Activity and Function of the PRMT8 Protein Arginine Methyltransferase in Neurons
por: Rui Dong, et al.
Publicado: (2021) -
Employing the EPEC Hierarchy of Conditions (Version II) To Evaluate the Effectiveness of Using Synchronous Technologies with Multi-Location Student Cohorts in the Tertiary Education Setting
por: Michelle Jean Eady, et al.
Publicado: (2017) -
14-3-3 Regulates Actin Filament Formation in the Deep-Branching Eukaryote <named-content content-type="genus-species">Giardia lamblia</named-content>
por: Jana Krtková, et al.
Publicado: (2017)