A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs

A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs

It is often difficult to identify functional SNPs from disease-associated SNPs in linkage disequilibrium. Here, the authors present Reel-seq, SDCP-MS and AIDP-Wb, three sequential methodologies for fSNP identification and characterization.

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Autores principales: Yihan Zhao, Di Wu, Danli Jiang, Xiaoyu Zhang, Ting Wu, Jing Cui, Min Qian, Jean Zhao, Steffi Oesterreich, Wei Sun, Toren Finkel, Gang Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/7e2afe32d69f4fc0b8f9d3871c094446
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spelling oai:doaj.org-article:7e2afe32d69f4fc0b8f9d3871c0944462021-12-02T16:32:09ZA sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs10.1038/s41467-020-17159-82041-1723https://doaj.org/article/7e2afe32d69f4fc0b8f9d3871c0944462020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17159-8https://doaj.org/toc/2041-1723It is often difficult to identify functional SNPs from disease-associated SNPs in linkage disequilibrium. Here, the authors present Reel-seq, SDCP-MS and AIDP-Wb, three sequential methodologies for fSNP identification and characterization.Yihan ZhaoDi WuDanli JiangXiaoyu ZhangTing WuJing CuiMin QianJean ZhaoSteffi OesterreichWei SunToren FinkelGang LiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yihan Zhao
Di Wu
Danli Jiang
Xiaoyu Zhang
Ting Wu
Jing Cui
Min Qian
Jean Zhao
Steffi Oesterreich
Wei Sun
Toren Finkel
Gang Li
A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs
description It is often difficult to identify functional SNPs from disease-associated SNPs in linkage disequilibrium. Here, the authors present Reel-seq, SDCP-MS and AIDP-Wb, three sequential methodologies for fSNP identification and characterization.
format article
author Yihan Zhao
Di Wu
Danli Jiang
Xiaoyu Zhang
Ting Wu
Jing Cui
Min Qian
Jean Zhao
Steffi Oesterreich
Wei Sun
Toren Finkel
Gang Li
author_facet Yihan Zhao
Di Wu
Danli Jiang
Xiaoyu Zhang
Ting Wu
Jing Cui
Min Qian
Jean Zhao
Steffi Oesterreich
Wei Sun
Toren Finkel
Gang Li
author_sort Yihan Zhao
title A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs
title_short A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs
title_full A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs
title_fullStr A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs
title_full_unstemmed A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs
title_sort sequential methodology for the rapid identification and characterization of breast cancer-associated functional snps
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/7e2afe32d69f4fc0b8f9d3871c094446
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