AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division

Pantazopoulou et al. find that AGO2 resides in open-ended tunneling nanotubes and close-ended cytokinetic bridges. At the latter location, AGO2 colocalizes with cell division components and the authors show that AGO2 depletion impairs cell division fidelity.

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Autores principales: Vasiliki I. Pantazopoulou, Anastasios D. Delis, Stella Georgiou, Stamatis N. Pagakis, Vicky Filippa, Eleni Dragona, Ismini Kloukina, Elias Chatzitheodoridis, Jonel Trebicka, Athanassios D. Velentzas, Maja Thiele, Sarantis Gagos, Dimitris Thanos, Sofia Tseleni-Balafouta, Dimitrios J. Stravopodis, Ema Anastasiadou
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7e2d246fce6f4d71b10947678754d0a9
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spelling oai:doaj.org-article:7e2d246fce6f4d71b10947678754d0a92021-12-02T17:34:48ZAGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division10.1038/s42003-021-02130-02399-3642https://doaj.org/article/7e2d246fce6f4d71b10947678754d0a92021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02130-0https://doaj.org/toc/2399-3642Pantazopoulou et al. find that AGO2 resides in open-ended tunneling nanotubes and close-ended cytokinetic bridges. At the latter location, AGO2 colocalizes with cell division components and the authors show that AGO2 depletion impairs cell division fidelity.Vasiliki I. PantazopoulouAnastasios D. DelisStella GeorgiouStamatis N. PagakisVicky FilippaEleni DragonaIsmini KloukinaElias ChatzitheodoridisJonel TrebickaAthanassios D. VelentzasMaja ThieleSarantis GagosDimitris ThanosSofia Tseleni-BalafoutaDimitrios J. StravopodisEma AnastasiadouNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Vasiliki I. Pantazopoulou
Anastasios D. Delis
Stella Georgiou
Stamatis N. Pagakis
Vicky Filippa
Eleni Dragona
Ismini Kloukina
Elias Chatzitheodoridis
Jonel Trebicka
Athanassios D. Velentzas
Maja Thiele
Sarantis Gagos
Dimitris Thanos
Sofia Tseleni-Balafouta
Dimitrios J. Stravopodis
Ema Anastasiadou
AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division
description Pantazopoulou et al. find that AGO2 resides in open-ended tunneling nanotubes and close-ended cytokinetic bridges. At the latter location, AGO2 colocalizes with cell division components and the authors show that AGO2 depletion impairs cell division fidelity.
format article
author Vasiliki I. Pantazopoulou
Anastasios D. Delis
Stella Georgiou
Stamatis N. Pagakis
Vicky Filippa
Eleni Dragona
Ismini Kloukina
Elias Chatzitheodoridis
Jonel Trebicka
Athanassios D. Velentzas
Maja Thiele
Sarantis Gagos
Dimitris Thanos
Sofia Tseleni-Balafouta
Dimitrios J. Stravopodis
Ema Anastasiadou
author_facet Vasiliki I. Pantazopoulou
Anastasios D. Delis
Stella Georgiou
Stamatis N. Pagakis
Vicky Filippa
Eleni Dragona
Ismini Kloukina
Elias Chatzitheodoridis
Jonel Trebicka
Athanassios D. Velentzas
Maja Thiele
Sarantis Gagos
Dimitris Thanos
Sofia Tseleni-Balafouta
Dimitrios J. Stravopodis
Ema Anastasiadou
author_sort Vasiliki I. Pantazopoulou
title AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division
title_short AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division
title_full AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division
title_fullStr AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division
title_full_unstemmed AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division
title_sort ago2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/7e2d246fce6f4d71b10947678754d0a9
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