Identification of FDA-approved antivirulence drugs targeting the Pseudomonas aeruginosa quorum sensing effector protein PqsE

The ability of the bacterial pathogen Pseudomonas aeruginosa to cause both chronic and acute infections mainly relies on its capacity to finely modulate the expression of virulence factors through a complex network of regulatory circuits, including the pqs quorum sensing (QS) system. While in most Q...

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Autores principales: Valerio Baldelli, Francesca D’Angelo, Viola Pavoncello, Ersilia Vita Fiscarelli, Paolo Visca, Giordano Rampioni, Livia Leoni
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2020
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Acceso en línea:https://doaj.org/article/7e2d2cbeaef94dbdacc17226a46ffa91
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