Functional polymorphisms of FAS and FASL gene and risk of breast cancer - pilot study of 134 cases.

Fas/Fas ligand (FasL) system is one of the key apoptotic signaling entities in the extrinsic apoptotic pathway. De-regulation of this pathway, i.e. by mutations may prevent the immune system from the removal of newly-formed tumor cells, and thus lead to tumor formation. The present study investigate...

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Auteurs principaux: Mohammad Hashemi, Aliakbar Fazaeli, Saeid Ghavami, Ebrahim Eskandari-Nasab, Farshid Arbabi, Mohammad Ali Mashhadi, Mohsen Taheri, Wiem Chaabane, Mayur V Jain, Marek J Łos
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/7e2d543571ef413db0b9f32ac554a79c
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