Expression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance

Objective. The development of obesity and its metabolic complications is associated with dys-regulation of various intrinsic mechanisms, which control basic metabolic processes via changes in the expression of numerous regulatory genes. The main goal of this work was to study the association between...

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Autores principales:	Minchenko Dmytro O., Tsymbal Dariia O., Davydov Vadim V., Minchenko Oleksandr H.
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2019
Materias:	mrna expression igfs igfbps htra1 blood obesity insulin resistance Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/7e3f07403f36456ea926a39f7a2a7d6e
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id	oai:doaj.org-article:7e3f07403f36456ea926a39f7a2a7d6e
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spelling	oai:doaj.org-article:7e3f07403f36456ea926a39f7a2a7d6e2021-12-02T16:41:14ZExpression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance1336-032910.2478/enr-2019-0005https://doaj.org/article/7e3f07403f36456ea926a39f7a2a7d6e2019-01-01T00:00:00Zhttps://doi.org/10.2478/enr-2019-0005https://doaj.org/toc/1336-0329Objective. The development of obesity and its metabolic complications is associated with dys-regulation of various intrinsic mechanisms, which control basic metabolic processes via changes in the expression of numerous regulatory genes. The main goal of this work was to study the association between the expression of insulin-like growth factors (IGF1 and IGF2) and IGF-binding proteins and insulin resistance in obese adolescents for evaluation of possible contribution of these genes in development of insulin resistance.Minchenko Dmytro O.Tsymbal Dariia O.Davydov Vadim V.Minchenko Oleksandr H.Sciendoarticlemrna expressionigfsigfbpshtra1bloodobesityinsulin resistanceDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 53, Iss 1, Pp 34-45 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	mrna expression igfs igfbps htra1 blood obesity insulin resistance Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	mrna expression igfs igfbps htra1 blood obesity insulin resistance Diseases of the endocrine glands. Clinical endocrinology RC648-665 Minchenko Dmytro O. Tsymbal Dariia O. Davydov Vadim V. Minchenko Oleksandr H. Expression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance
description	Objective. The development of obesity and its metabolic complications is associated with dys-regulation of various intrinsic mechanisms, which control basic metabolic processes via changes in the expression of numerous regulatory genes. The main goal of this work was to study the association between the expression of insulin-like growth factors (IGF1 and IGF2) and IGF-binding proteins and insulin resistance in obese adolescents for evaluation of possible contribution of these genes in development of insulin resistance.
format	article
author	Minchenko Dmytro O. Tsymbal Dariia O. Davydov Vadim V. Minchenko Oleksandr H.
author_facet	Minchenko Dmytro O. Tsymbal Dariia O. Davydov Vadim V. Minchenko Oleksandr H.
author_sort	Minchenko Dmytro O.
title	Expression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance
title_short	Expression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance
title_full	Expression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance
title_fullStr	Expression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance
title_full_unstemmed	Expression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance
title_sort	expression of genes encoding igf1, igf2, and igfbps in blood of obese adolescents with insulin resistance
publisher	Sciendo
publishDate	2019
url	https://doaj.org/article/7e3f07403f36456ea926a39f7a2a7d6e
work_keys_str_mv	AT minchenkodmytroo expressionofgenesencodingigf1igf2andigfbpsinbloodofobeseadolescentswithinsulinresistance AT tsymbaldariiao expressionofgenesencodingigf1igf2andigfbpsinbloodofobeseadolescentswithinsulinresistance AT davydovvadimv expressionofgenesencodingigf1igf2andigfbpsinbloodofobeseadolescentswithinsulinresistance AT minchenkooleksandrh expressionofgenesencodingigf1igf2andigfbpsinbloodofobeseadolescentswithinsulinresistance
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Expression of genes encoding IGF1, IGF2, and IGFBPs in blood of obese adolescents with insulin resistance

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