Thermal stress triggers broad Pocillopora damicornis transcriptomic remodeling, while Vibrio coralliilyticus infection induces a more targeted immuno-suppression response.

Global change and its associated temperature increase has directly or indirectly changed the distributions of hosts and pathogens, and has affected host immunity, pathogen virulence and growth rates. This has resulted in increased disease in natural plant and animal populations worldwide, including...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jeremie Vidal-Dupiol, Nolwenn M Dheilly, Rodolfo Rondon, Christoph Grunau, Céline Cosseau, Kristina M Smith, Michael Freitag, Mehdi Adjeroud, Guillaume Mitta
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7e42850aeda94b5bb1991fa2f81a6dd8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7e42850aeda94b5bb1991fa2f81a6dd8
record_format	dspace
spelling	oai:doaj.org-article:7e42850aeda94b5bb1991fa2f81a6dd82021-11-25T05:59:10ZThermal stress triggers broad Pocillopora damicornis transcriptomic remodeling, while Vibrio coralliilyticus infection induces a more targeted immuno-suppression response.1932-620310.1371/journal.pone.0107672https://doaj.org/article/7e42850aeda94b5bb1991fa2f81a6dd82014-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0107672https://doaj.org/toc/1932-6203Global change and its associated temperature increase has directly or indirectly changed the distributions of hosts and pathogens, and has affected host immunity, pathogen virulence and growth rates. This has resulted in increased disease in natural plant and animal populations worldwide, including scleractinian corals. While the effects of temperature increase on immunity and pathogen virulence have been clearly identified, their interaction, synergy and relative weight during pathogenesis remain poorly documented. We investigated these phenomena in the interaction between the coral Pocillopora damicornis and the bacterium Vibrio coralliilyticus, for which the infection process is temperature-dependent. We developed an experimental model that enabled unraveling the effects of thermal stress, and virulence vs. non-virulence of the bacterium. The physiological impacts of various treatments were quantified at the transcriptome level using a combination of RNA sequencing and targeted approaches. The results showed that thermal stress triggered a general weakening of the coral, making it more prone to infection, non-virulent bacterium induced an 'efficient' immune response, whereas virulent bacterium caused immuno-suppression in its host.Jeremie Vidal-DupiolNolwenn M DheillyRodolfo RondonChristoph GrunauCéline CosseauKristina M SmithMichael FreitagMehdi AdjeroudGuillaume MittaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 9, p e107672 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jeremie Vidal-Dupiol Nolwenn M Dheilly Rodolfo Rondon Christoph Grunau Céline Cosseau Kristina M Smith Michael Freitag Mehdi Adjeroud Guillaume Mitta Thermal stress triggers broad Pocillopora damicornis transcriptomic remodeling, while Vibrio coralliilyticus infection induces a more targeted immuno-suppression response.
description	Global change and its associated temperature increase has directly or indirectly changed the distributions of hosts and pathogens, and has affected host immunity, pathogen virulence and growth rates. This has resulted in increased disease in natural plant and animal populations worldwide, including scleractinian corals. While the effects of temperature increase on immunity and pathogen virulence have been clearly identified, their interaction, synergy and relative weight during pathogenesis remain poorly documented. We investigated these phenomena in the interaction between the coral Pocillopora damicornis and the bacterium Vibrio coralliilyticus, for which the infection process is temperature-dependent. We developed an experimental model that enabled unraveling the effects of thermal stress, and virulence vs. non-virulence of the bacterium. The physiological impacts of various treatments were quantified at the transcriptome level using a combination of RNA sequencing and targeted approaches. The results showed that thermal stress triggered a general weakening of the coral, making it more prone to infection, non-virulent bacterium induced an 'efficient' immune response, whereas virulent bacterium caused immuno-suppression in its host.
format	article
author	Jeremie Vidal-Dupiol Nolwenn M Dheilly Rodolfo Rondon Christoph Grunau Céline Cosseau Kristina M Smith Michael Freitag Mehdi Adjeroud Guillaume Mitta
author_facet	Jeremie Vidal-Dupiol Nolwenn M Dheilly Rodolfo Rondon Christoph Grunau Céline Cosseau Kristina M Smith Michael Freitag Mehdi Adjeroud Guillaume Mitta
author_sort	Jeremie Vidal-Dupiol
title	Thermal stress triggers broad Pocillopora damicornis transcriptomic remodeling, while Vibrio coralliilyticus infection induces a more targeted immuno-suppression response.
title_short	Thermal stress triggers broad Pocillopora damicornis transcriptomic remodeling, while Vibrio coralliilyticus infection induces a more targeted immuno-suppression response.
title_full	Thermal stress triggers broad Pocillopora damicornis transcriptomic remodeling, while Vibrio coralliilyticus infection induces a more targeted immuno-suppression response.
title_fullStr	Thermal stress triggers broad Pocillopora damicornis transcriptomic remodeling, while Vibrio coralliilyticus infection induces a more targeted immuno-suppression response.
title_full_unstemmed	Thermal stress triggers broad Pocillopora damicornis transcriptomic remodeling, while Vibrio coralliilyticus infection induces a more targeted immuno-suppression response.
title_sort	thermal stress triggers broad pocillopora damicornis transcriptomic remodeling, while vibrio coralliilyticus infection induces a more targeted immuno-suppression response.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/7e42850aeda94b5bb1991fa2f81a6dd8
work_keys_str_mv	AT jeremievidaldupiol thermalstresstriggersbroadpocilloporadamicornistranscriptomicremodelingwhilevibriocoralliilyticusinfectioninducesamoretargetedimmunosuppressionresponse AT nolwennmdheilly thermalstresstriggersbroadpocilloporadamicornistranscriptomicremodelingwhilevibriocoralliilyticusinfectioninducesamoretargetedimmunosuppressionresponse AT rodolforondon thermalstresstriggersbroadpocilloporadamicornistranscriptomicremodelingwhilevibriocoralliilyticusinfectioninducesamoretargetedimmunosuppressionresponse AT christophgrunau thermalstresstriggersbroadpocilloporadamicornistranscriptomicremodelingwhilevibriocoralliilyticusinfectioninducesamoretargetedimmunosuppressionresponse AT celinecosseau thermalstresstriggersbroadpocilloporadamicornistranscriptomicremodelingwhilevibriocoralliilyticusinfectioninducesamoretargetedimmunosuppressionresponse AT kristinamsmith thermalstresstriggersbroadpocilloporadamicornistranscriptomicremodelingwhilevibriocoralliilyticusinfectioninducesamoretargetedimmunosuppressionresponse AT michaelfreitag thermalstresstriggersbroadpocilloporadamicornistranscriptomicremodelingwhilevibriocoralliilyticusinfectioninducesamoretargetedimmunosuppressionresponse AT mehdiadjeroud thermalstresstriggersbroadpocilloporadamicornistranscriptomicremodelingwhilevibriocoralliilyticusinfectioninducesamoretargetedimmunosuppressionresponse AT guillaumemitta thermalstresstriggersbroadpocilloporadamicornistranscriptomicremodelingwhilevibriocoralliilyticusinfectioninducesamoretargetedimmunosuppressionresponse
_version_	1718414350746648576

Thermal stress triggers broad Pocillopora damicornis transcriptomic remodeling, while Vibrio coralliilyticus infection induces a more targeted immuno-suppression response.

Ejemplares similares