The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo

The physiological role of prion-like domains (PLDs) within RNA-binding proteins is not well understood. Here, authors show in Drosophila that the PLD in the protein Imp is required for localization of ribonucleoprotein granules to axons and axonal remodelling.

Guardado en:

Detalles Bibliográficos
Autores principales:	Jeshlee Vijayakumar, Charlène Perrois, Marjorie Heim, Luc Bousset, Simon Alberti, Florence Besse
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7e4464bf3ee646c6b0abe6341292c927
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7e4464bf3ee646c6b0abe6341292c927
record_format	dspace
spelling	oai:doaj.org-article:7e4464bf3ee646c6b0abe6341292c9272021-12-02T17:01:53ZThe prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo10.1038/s41467-019-10554-w2041-1723https://doaj.org/article/7e4464bf3ee646c6b0abe6341292c9272019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10554-whttps://doaj.org/toc/2041-1723The physiological role of prion-like domains (PLDs) within RNA-binding proteins is not well understood. Here, authors show in Drosophila that the PLD in the protein Imp is required for localization of ribonucleoprotein granules to axons and axonal remodelling.Jeshlee VijayakumarCharlène PerroisMarjorie HeimLuc BoussetSimon AlbertiFlorence BesseNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jeshlee Vijayakumar Charlène Perrois Marjorie Heim Luc Bousset Simon Alberti Florence Besse The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo
description	The physiological role of prion-like domains (PLDs) within RNA-binding proteins is not well understood. Here, authors show in Drosophila that the PLD in the protein Imp is required for localization of ribonucleoprotein granules to axons and axonal remodelling.
format	article
author	Jeshlee Vijayakumar Charlène Perrois Marjorie Heim Luc Bousset Simon Alberti Florence Besse
author_facet	Jeshlee Vijayakumar Charlène Perrois Marjorie Heim Luc Bousset Simon Alberti Florence Besse
author_sort	Jeshlee Vijayakumar
title	The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo
title_short	The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo
title_full	The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo
title_fullStr	The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo
title_full_unstemmed	The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo
title_sort	prion-like domain of drosophila imp promotes axonal transport of rnp granules in vivo
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/7e4464bf3ee646c6b0abe6341292c927
work_keys_str_mv	AT jeshleevijayakumar theprionlikedomainofdrosophilaimppromotesaxonaltransportofrnpgranulesinvivo AT charleneperrois theprionlikedomainofdrosophilaimppromotesaxonaltransportofrnpgranulesinvivo AT marjorieheim theprionlikedomainofdrosophilaimppromotesaxonaltransportofrnpgranulesinvivo AT lucbousset theprionlikedomainofdrosophilaimppromotesaxonaltransportofrnpgranulesinvivo AT simonalberti theprionlikedomainofdrosophilaimppromotesaxonaltransportofrnpgranulesinvivo AT florencebesse theprionlikedomainofdrosophilaimppromotesaxonaltransportofrnpgranulesinvivo AT jeshleevijayakumar prionlikedomainofdrosophilaimppromotesaxonaltransportofrnpgranulesinvivo AT charleneperrois prionlikedomainofdrosophilaimppromotesaxonaltransportofrnpgranulesinvivo AT marjorieheim prionlikedomainofdrosophilaimppromotesaxonaltransportofrnpgranulesinvivo AT lucbousset prionlikedomainofdrosophilaimppromotesaxonaltransportofrnpgranulesinvivo AT simonalberti prionlikedomainofdrosophilaimppromotesaxonaltransportofrnpgranulesinvivo AT florencebesse prionlikedomainofdrosophilaimppromotesaxonaltransportofrnpgranulesinvivo
_version_	1718382037032763392

The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo

Ejemplares similares