The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo

The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo

The physiological role of prion-like domains (PLDs) within RNA-binding proteins is not well understood. Here, authors show in Drosophila that the PLD in the protein Imp is required for localization of ribonucleoprotein granules to axons and axonal remodelling.

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Autores principales: Jeshlee Vijayakumar, Charlène Perrois, Marjorie Heim, Luc Bousset, Simon Alberti, Florence Besse
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/7e4464bf3ee646c6b0abe6341292c927
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