A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis

Programmed cell death or apoptosis is an essential biological process that is impaired in some diseases and can be used to assess the effectiveness of drugs. Here the authors design Apo-15 as a fluorogenic peptide for the detection and real-time imaging of apoptotic cells.

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Autores principales:	Nicole D. Barth, Ramon Subiros-Funosas, Lorena Mendive-Tapia, Rodger Duffin, Mario A. Shields, Jennifer A. Cartwright, Sónia Troeira Henriques, Jesus Sot, Felix M. Goñi, Rodolfo Lavilla, John A. Marwick, Sonja Vermeren, Adriano G. Rossi, Mikala Egeblad, Ian Dransfield, Marc Vendrell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7e4b972f90a04057803fb05db7c472e8
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spelling	oai:doaj.org-article:7e4b972f90a04057803fb05db7c472e82021-12-02T18:51:02ZA fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis10.1038/s41467-020-17772-72041-1723https://doaj.org/article/7e4b972f90a04057803fb05db7c472e82020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17772-7https://doaj.org/toc/2041-1723Programmed cell death or apoptosis is an essential biological process that is impaired in some diseases and can be used to assess the effectiveness of drugs. Here the authors design Apo-15 as a fluorogenic peptide for the detection and real-time imaging of apoptotic cells.Nicole D. BarthRamon Subiros-FunosasLorena Mendive-TapiaRodger DuffinMario A. ShieldsJennifer A. CartwrightSónia Troeira HenriquesJesus SotFelix M. GoñiRodolfo LavillaJohn A. MarwickSonja VermerenAdriano G. RossiMikala EgebladIan DransfieldMarc VendrellNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nicole D. Barth Ramon Subiros-Funosas Lorena Mendive-Tapia Rodger Duffin Mario A. Shields Jennifer A. Cartwright Sónia Troeira Henriques Jesus Sot Felix M. Goñi Rodolfo Lavilla John A. Marwick Sonja Vermeren Adriano G. Rossi Mikala Egeblad Ian Dransfield Marc Vendrell A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis
description	Programmed cell death or apoptosis is an essential biological process that is impaired in some diseases and can be used to assess the effectiveness of drugs. Here the authors design Apo-15 as a fluorogenic peptide for the detection and real-time imaging of apoptotic cells.
format	article
author	Nicole D. Barth Ramon Subiros-Funosas Lorena Mendive-Tapia Rodger Duffin Mario A. Shields Jennifer A. Cartwright Sónia Troeira Henriques Jesus Sot Felix M. Goñi Rodolfo Lavilla John A. Marwick Sonja Vermeren Adriano G. Rossi Mikala Egeblad Ian Dransfield Marc Vendrell
author_facet	Nicole D. Barth Ramon Subiros-Funosas Lorena Mendive-Tapia Rodger Duffin Mario A. Shields Jennifer A. Cartwright Sónia Troeira Henriques Jesus Sot Felix M. Goñi Rodolfo Lavilla John A. Marwick Sonja Vermeren Adriano G. Rossi Mikala Egeblad Ian Dransfield Marc Vendrell
author_sort	Nicole D. Barth
title	A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis
title_short	A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis
title_full	A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis
title_fullStr	A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis
title_full_unstemmed	A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis
title_sort	fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7e4b972f90a04057803fb05db7c472e8
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A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis

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