CD32 expression is associated to T-cell activation and is not a marker of the HIV-1 reservoir

CD32 has been previously shown to be expressed preferentially by CD4 T cells latently harbouring HIV-1. Here the authors show that CD32 expression in CD4 T cells is associated with T cell activation, is up-regulated by HIV-1 infection and importantly does not appear to represent an enriched cellular...

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Autores principales: Roger Badia, Ester Ballana, Marc Castellví, Edurne García-Vidal, Maria Pujantell, Bonaventura Clotet, Julia G. Prado, Jordi Puig, Miguel A. Martínez, Eva Riveira-Muñoz, José A. Esté
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/7e50053306594d9bbbe279cb0c8a7902
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spelling oai:doaj.org-article:7e50053306594d9bbbe279cb0c8a79022021-12-02T14:40:31ZCD32 expression is associated to T-cell activation and is not a marker of the HIV-1 reservoir10.1038/s41467-018-05157-w2041-1723https://doaj.org/article/7e50053306594d9bbbe279cb0c8a79022018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05157-whttps://doaj.org/toc/2041-1723CD32 has been previously shown to be expressed preferentially by CD4 T cells latently harbouring HIV-1. Here the authors show that CD32 expression in CD4 T cells is associated with T cell activation, is up-regulated by HIV-1 infection and importantly does not appear to represent an enriched cellular niche for latent HIV-1.Roger BadiaEster BallanaMarc CastellvíEdurne García-VidalMaria PujantellBonaventura ClotetJulia G. PradoJordi PuigMiguel A. MartínezEva Riveira-MuñozJosé A. EstéNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Roger Badia
Ester Ballana
Marc Castellví
Edurne García-Vidal
Maria Pujantell
Bonaventura Clotet
Julia G. Prado
Jordi Puig
Miguel A. Martínez
Eva Riveira-Muñoz
José A. Esté
CD32 expression is associated to T-cell activation and is not a marker of the HIV-1 reservoir
description CD32 has been previously shown to be expressed preferentially by CD4 T cells latently harbouring HIV-1. Here the authors show that CD32 expression in CD4 T cells is associated with T cell activation, is up-regulated by HIV-1 infection and importantly does not appear to represent an enriched cellular niche for latent HIV-1.
format article
author Roger Badia
Ester Ballana
Marc Castellví
Edurne García-Vidal
Maria Pujantell
Bonaventura Clotet
Julia G. Prado
Jordi Puig
Miguel A. Martínez
Eva Riveira-Muñoz
José A. Esté
author_facet Roger Badia
Ester Ballana
Marc Castellví
Edurne García-Vidal
Maria Pujantell
Bonaventura Clotet
Julia G. Prado
Jordi Puig
Miguel A. Martínez
Eva Riveira-Muñoz
José A. Esté
author_sort Roger Badia
title CD32 expression is associated to T-cell activation and is not a marker of the HIV-1 reservoir
title_short CD32 expression is associated to T-cell activation and is not a marker of the HIV-1 reservoir
title_full CD32 expression is associated to T-cell activation and is not a marker of the HIV-1 reservoir
title_fullStr CD32 expression is associated to T-cell activation and is not a marker of the HIV-1 reservoir
title_full_unstemmed CD32 expression is associated to T-cell activation and is not a marker of the HIV-1 reservoir
title_sort cd32 expression is associated to t-cell activation and is not a marker of the hiv-1 reservoir
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/7e50053306594d9bbbe279cb0c8a7902
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