Epithelial to Mesenchymal Transition: Key Regulator of Pancreatic Ductal Adenocarcinoma Progression and Chemoresistance

Epithelial to Mesenchymal Transition: Key Regulator of Pancreatic Ductal Adenocarcinoma Progression and Chemoresistance

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies, characterized by aggressive biological behavior and a lack of response to currently available chemotherapy. Emerging evidence has identified epithelial to mesenchymal transition (EMT) as a key driver of PDAC progression an...

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Bibliographic Details
Main Authors: Kostas Palamaris, Evangelos Felekouras, Stratigoula Sakellariou
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
pancreatic ductal adenocarcinoma
epithelial to mesenchymal transition
cancer stem cells
intratumor heterogeneity
tumor microenvironment
chemoresistance
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/7e5ad0ffe3884d85ae1ff2f7a8f1c09d
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https://doaj.org/article/7e5ad0ffe3884d85ae1ff2f7a8f1c09d

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