PLK1 protects against sepsis-induced intestinal barrier dysfunction
Abstract Sepsis and sepsis-associated intestinal barrier dysfunction are common in intensive care units, with high mortality. The aim of this study is to investigate whether Polo-like kinase 1 (PLK1) ameliorates sepsis-induced intestinal barrier dysfunction in the intestinal epithelium. The mouse in...
Saved in:
Main Authors: | Yingya Cao, Qun Chen, Zhen Wang, Tao Yu, Jingyi Wu, Xiaogan Jiang, Xiaoju Jin, Weihua Lu |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
|
Subjects: | |
Online Access: | https://doaj.org/article/7e63f768a0bb4f0a9fb1b82146717c3a |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Systemic blockade of P2X7 receptor protects against sepsis-induced intestinal barrier disruption
by: Xiuwen Wu, et al.
Published: (2017) -
Intermedin protects against sepsis by concurrently re-establishing the endothelial barrier and alleviating inflammatory responses
by: Fei Xiao, et al.
Published: (2018) -
Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction
by: Eirini Giannoudaki, et al.
Published: (2019) -
Tongxinluo prevents chronic obstructive pulmonary disease complicated with atherosclerosis by inhibiting ferroptosis and protecting against pulmonary microvascular barrier dysfunction
by: Yafen Wang, et al.
Published: (2022) -
STING protects against cardiac dysfunction and remodelling by blocking autophagy
by: Rui Xiong, et al.
Published: (2021)