Leucovorin Enhances the Anti-cancer Effect of Bortezomib in Colorectal Cancer Cells

Abstract Colorectal cancer is a major cancer type worldwide. 5-fluorouracil, often given with leucovorin, is the most commonly used drug in colorectal cancer chemotherapy, yet development of drug resistance to 5-fluorouracil in colorectal cancer cells is the primary cause of chemotherapy failure. Mo...

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Bibliographic Details
Main Authors: Shu Wang, Lei Wang, Zhiyang Zhou, Qipan Deng, Ling Li, Mingzhi Zhang, Linlin Liu, Yong Li
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/7e6684641dae4958a4e0e768366c3204
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