Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis

Caveolae are plasma membrane invaginations containing cavin proteins that are disrupted upon stress stimuli, causing cavin release inside the cell. Here, McMahon et al. identify cavin interacting proteins using proteomic analyses and reveal functions in stress signaling that can promote apoptosis.

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Autores principales:	Kerrie-Ann McMahon, Yeping Wu, Yann Gambin, Emma Sierecki, Vikas A. Tillu, Thomas Hall, Nick Martel, Satomi Okano, Shayli Varasteh Moradi, Jayde E. Ruelcke, Charles Ferguson, Alpha S. Yap, Kirill Alexandrov, Michelle M. Hill, Robert G. Parton
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7e714ae10b044f39b3b19d07f1029486
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spelling	oai:doaj.org-article:7e714ae10b044f39b3b19d07f10294862021-12-02T16:58:25ZIdentification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis10.1038/s41467-019-11111-12041-1723https://doaj.org/article/7e714ae10b044f39b3b19d07f10294862019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11111-1https://doaj.org/toc/2041-1723Caveolae are plasma membrane invaginations containing cavin proteins that are disrupted upon stress stimuli, causing cavin release inside the cell. Here, McMahon et al. identify cavin interacting proteins using proteomic analyses and reveal functions in stress signaling that can promote apoptosis.Kerrie-Ann McMahonYeping WuYann GambinEmma SiereckiVikas A. TilluThomas HallNick MartelSatomi OkanoShayli Varasteh MoradiJayde E. RuelckeCharles FergusonAlpha S. YapKirill AlexandrovMichelle M. HillRobert G. PartonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kerrie-Ann McMahon Yeping Wu Yann Gambin Emma Sierecki Vikas A. Tillu Thomas Hall Nick Martel Satomi Okano Shayli Varasteh Moradi Jayde E. Ruelcke Charles Ferguson Alpha S. Yap Kirill Alexandrov Michelle M. Hill Robert G. Parton Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis
description	Caveolae are plasma membrane invaginations containing cavin proteins that are disrupted upon stress stimuli, causing cavin release inside the cell. Here, McMahon et al. identify cavin interacting proteins using proteomic analyses and reveal functions in stress signaling that can promote apoptosis.
format	article
author	Kerrie-Ann McMahon Yeping Wu Yann Gambin Emma Sierecki Vikas A. Tillu Thomas Hall Nick Martel Satomi Okano Shayli Varasteh Moradi Jayde E. Ruelcke Charles Ferguson Alpha S. Yap Kirill Alexandrov Michelle M. Hill Robert G. Parton
author_facet	Kerrie-Ann McMahon Yeping Wu Yann Gambin Emma Sierecki Vikas A. Tillu Thomas Hall Nick Martel Satomi Okano Shayli Varasteh Moradi Jayde E. Ruelcke Charles Ferguson Alpha S. Yap Kirill Alexandrov Michelle M. Hill Robert G. Parton
author_sort	Kerrie-Ann McMahon
title	Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis
title_short	Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis
title_full	Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis
title_fullStr	Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis
title_full_unstemmed	Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis
title_sort	identification of intracellular cavin target proteins reveals cavin-pp1alpha interactions regulate apoptosis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/7e714ae10b044f39b3b19d07f1029486
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Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis

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