TRPA1-Mediated Src Family Kinases Activity Facilitates Cortical Spreading Depression Susceptibility and Trigeminovascular System Sensitization
Transient receptor potential ankyrin 1 (TRPA1) plays a role in migraine and is proposed as a promising target for migraine therapy. However, TRPA1-induced signaling in migraine pathogenesis is poorly understood. In this study, we explored the hypothesis that Src family kinases (SFKs) transmit TRPA1...
Guardado en:
Autores principales: | Lingdi Nie, Liwen Jiang, John P. Quinn, Blair D. Grubb, Minyan Wang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7e720fcaeea84a5a814f6839da0a01de |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Src family kinases activity is required for transmitting purinergic P2X7 receptor signaling in cortical spreading depression and neuroinflammation
por: Lingdi Nie, et al.
Publicado: (2021) -
Downregulation of Src-family tyrosine kinases by Srcasm and c-Cbl: A comparative analysis
por: Vivian Lee, et al.
Publicado: (2021) -
Brainstem and Cortical Spreading Depolarization in a Closed Head Injury Rat Model
por: Refat Aboghazleh, et al.
Publicado: (2021) -
Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5
por: Viggiano E, et al.
Publicado: (2016) -
The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early <named-content content-type="genus-species">Chlamydia trachomatis</named-content> Vacuoles
por: Victoria Carpenter, et al.
Publicado: (2017)