Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure

SPX proteins sense phosphate levels in plant cells by binding to inositol polyphosphates (InsP) and suppressing the activity of PHR transcription factors. Here the authors show that when bound to InsP6, the rice SPX1 protein inhibits the activity of PHR2 by attenuating both its dimerization and DNA...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jia Zhou, Qinli Hu, Xinlong Xiao, Deqiang Yao, Shenghong Ge, Jin Ye, Haojie Li, Rujie Cai, Renyang Liu, Fangang Meng, Chao Wang, Jian-Kang Zhu, Mingguang Lei, Weiman Xing
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7e7322d6ae8844aca07f3af1249f3cf5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7e7322d6ae8844aca07f3af1249f3cf5
record_format	dspace
spelling	oai:doaj.org-article:7e7322d6ae8844aca07f3af1249f3cf52021-12-05T12:21:46ZMechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure10.1038/s41467-021-27391-52041-1723https://doaj.org/article/7e7322d6ae8844aca07f3af1249f3cf52021-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27391-5https://doaj.org/toc/2041-1723SPX proteins sense phosphate levels in plant cells by binding to inositol polyphosphates (InsP) and suppressing the activity of PHR transcription factors. Here the authors show that when bound to InsP6, the rice SPX1 protein inhibits the activity of PHR2 by attenuating both its dimerization and DNA binding activity.Jia ZhouQinli HuXinlong XiaoDeqiang YaoShenghong GeJin YeHaojie LiRujie CaiRenyang LiuFangang MengChao WangJian-Kang ZhuMingguang LeiWeiman XingNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jia Zhou Qinli Hu Xinlong Xiao Deqiang Yao Shenghong Ge Jin Ye Haojie Li Rujie Cai Renyang Liu Fangang Meng Chao Wang Jian-Kang Zhu Mingguang Lei Weiman Xing Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure
description	SPX proteins sense phosphate levels in plant cells by binding to inositol polyphosphates (InsP) and suppressing the activity of PHR transcription factors. Here the authors show that when bound to InsP6, the rice SPX1 protein inhibits the activity of PHR2 by attenuating both its dimerization and DNA binding activity.
format	article
author	Jia Zhou Qinli Hu Xinlong Xiao Deqiang Yao Shenghong Ge Jin Ye Haojie Li Rujie Cai Renyang Liu Fangang Meng Chao Wang Jian-Kang Zhu Mingguang Lei Weiman Xing
author_facet	Jia Zhou Qinli Hu Xinlong Xiao Deqiang Yao Shenghong Ge Jin Ye Haojie Li Rujie Cai Renyang Liu Fangang Meng Chao Wang Jian-Kang Zhu Mingguang Lei Weiman Xing
author_sort	Jia Zhou
title	Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure
title_short	Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure
title_full	Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure
title_fullStr	Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure
title_full_unstemmed	Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure
title_sort	mechanism of phosphate sensing and signaling revealed by rice spx1-phr2 complex structure
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7e7322d6ae8844aca07f3af1249f3cf5
work_keys_str_mv	AT jiazhou mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT qinlihu mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT xinlongxiao mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT deqiangyao mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT shenghongge mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT jinye mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT haojieli mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT rujiecai mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT renyangliu mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT fangangmeng mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT chaowang mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT jiankangzhu mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT mingguanglei mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure AT weimanxing mechanismofphosphatesensingandsignalingrevealedbyricespx1phr2complexstructure
_version_	1718372026252525568

Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure

Ejemplares similares