Links and risks associated with psoriasis and metabolic syndrome

Aikaterini I Liakou, Christos C Zouboulis Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Centre, Dessau, Germany Introduction: Psoriasis has long been considered a systemic inflammatory disease. Lately, it has been strongly associated with obesity, as well as ot...

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Autores principales:	Liakou AI, Zouboulis CC
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/7e78f87012c74420a02f034ab7b1d278
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spelling	oai:doaj.org-article:7e78f87012c74420a02f034ab7b1d2782021-12-02T02:57:07ZLinks and risks associated with psoriasis and metabolic syndrome2230-326Xhttps://doaj.org/article/7e78f87012c74420a02f034ab7b1d2782015-11-01T00:00:00Zhttps://www.dovepress.com/links-and-risks-associated-with-psoriasis-and-metabolic-syndrome-peer-reviewed-article-PTThttps://doaj.org/toc/2230-326XAikaterini I Liakou, Christos C Zouboulis Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Centre, Dessau, Germany Introduction: Psoriasis has long been considered a systemic inflammatory disease. Lately, it has been strongly associated with obesity, as well as other components of metabolic syndrome, such as dyslipidemia, insulin resistance, and arterial hypertension. Methods: We reviewed the literature of the last decade by using the keywords: psoriasis, metabolic syndrome, and/or obesity in PubMed and Medline. Results: Obesity and psoriasis seem to share similar profiles of systemic inflammation. Serum cytokines such as TNF-α, CRP, IL-6, and IL-12 are elevated in both disorders. The more severely an individual is affected with psoriasis, the more likely it is to be obese. This makes the disease an important health care issue, which requires the cooperation of dermatologists with other medical specialists. Discussion: This review attempts to summarize the links and risks that associate psoriasis with obesity, and highlight the concerns and queries for both disorders in the future. Keywords: psoriasis, obesity, metabolic, syndrome, inflammationLiakou AIZouboulis CCDove Medical PressarticleDermatologyRL1-803ENPsoriasis: Targets and Therapy, Vol 2015, Iss default, Pp 125-128 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Dermatology RL1-803
spellingShingle	Dermatology RL1-803 Liakou AI Zouboulis CC Links and risks associated with psoriasis and metabolic syndrome
description	Aikaterini I Liakou, Christos C Zouboulis Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Centre, Dessau, Germany Introduction: Psoriasis has long been considered a systemic inflammatory disease. Lately, it has been strongly associated with obesity, as well as other components of metabolic syndrome, such as dyslipidemia, insulin resistance, and arterial hypertension. Methods: We reviewed the literature of the last decade by using the keywords: psoriasis, metabolic syndrome, and/or obesity in PubMed and Medline. Results: Obesity and psoriasis seem to share similar profiles of systemic inflammation. Serum cytokines such as TNF-α, CRP, IL-6, and IL-12 are elevated in both disorders. The more severely an individual is affected with psoriasis, the more likely it is to be obese. This makes the disease an important health care issue, which requires the cooperation of dermatologists with other medical specialists. Discussion: This review attempts to summarize the links and risks that associate psoriasis with obesity, and highlight the concerns and queries for both disorders in the future. Keywords: psoriasis, obesity, metabolic, syndrome, inflammation
format	article
author	Liakou AI Zouboulis CC
author_facet	Liakou AI Zouboulis CC
author_sort	Liakou AI
title	Links and risks associated with psoriasis and metabolic syndrome
title_short	Links and risks associated with psoriasis and metabolic syndrome
title_full	Links and risks associated with psoriasis and metabolic syndrome
title_fullStr	Links and risks associated with psoriasis and metabolic syndrome
title_full_unstemmed	Links and risks associated with psoriasis and metabolic syndrome
title_sort	links and risks associated with psoriasis and metabolic syndrome
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/7e78f87012c74420a02f034ab7b1d278
work_keys_str_mv	AT liakouai linksandrisksassociatedwithpsoriasisandmetabolicsyndrome AT zoubouliscc linksandrisksassociatedwithpsoriasisandmetabolicsyndrome
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Links and risks associated with psoriasis and metabolic syndrome

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