Intestinal fungi are causally implicated in microbiome assembly and immune development in mice

The immunomodulatory role of commensal gut fungi and interactions with bacteria remain unclear. Here, using germ-free mice colonized with defined species of bacteria and fungi, the authors find that fungal colonization induces changes in bacterial microbiome ecology while having an independent effec...

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Autores principales:	Erik van Tilburg Bernardes, Veronika Kuchařová Pettersen, Mackenzie W. Gutierrez, Isabelle Laforest-Lapointe, Nicholas G. Jendzjowsky, Jean-Baptiste Cavin, Fernando A. Vicentini, Catherine M. Keenan, Hena R. Ramay, Jumana Samara, Wallace K. MacNaughton, Richard J. A. Wilson, Margaret M. Kelly, Kathy D. McCoy, Keith A. Sharkey, Marie-Claire Arrieta
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7e7a71db7d15468095e5d2a5ace43434
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spelling	oai:doaj.org-article:7e7a71db7d15468095e5d2a5ace434342021-12-02T16:51:25ZIntestinal fungi are causally implicated in microbiome assembly and immune development in mice10.1038/s41467-020-16431-12041-1723https://doaj.org/article/7e7a71db7d15468095e5d2a5ace434342020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16431-1https://doaj.org/toc/2041-1723The immunomodulatory role of commensal gut fungi and interactions with bacteria remain unclear. Here, using germ-free mice colonized with defined species of bacteria and fungi, the authors find that fungal colonization induces changes in bacterial microbiome ecology while having an independent effect on innate and adaptive immunity in mice.Erik van Tilburg BernardesVeronika Kuchařová PettersenMackenzie W. GutierrezIsabelle Laforest-LapointeNicholas G. JendzjowskyJean-Baptiste CavinFernando A. VicentiniCatherine M. KeenanHena R. RamayJumana SamaraWallace K. MacNaughtonRichard J. A. WilsonMargaret M. KellyKathy D. McCoyKeith A. SharkeyMarie-Claire ArrietaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erik van Tilburg Bernardes Veronika Kuchařová Pettersen Mackenzie W. Gutierrez Isabelle Laforest-Lapointe Nicholas G. Jendzjowsky Jean-Baptiste Cavin Fernando A. Vicentini Catherine M. Keenan Hena R. Ramay Jumana Samara Wallace K. MacNaughton Richard J. A. Wilson Margaret M. Kelly Kathy D. McCoy Keith A. Sharkey Marie-Claire Arrieta Intestinal fungi are causally implicated in microbiome assembly and immune development in mice
description	The immunomodulatory role of commensal gut fungi and interactions with bacteria remain unclear. Here, using germ-free mice colonized with defined species of bacteria and fungi, the authors find that fungal colonization induces changes in bacterial microbiome ecology while having an independent effect on innate and adaptive immunity in mice.
format	article
author	Erik van Tilburg Bernardes Veronika Kuchařová Pettersen Mackenzie W. Gutierrez Isabelle Laforest-Lapointe Nicholas G. Jendzjowsky Jean-Baptiste Cavin Fernando A. Vicentini Catherine M. Keenan Hena R. Ramay Jumana Samara Wallace K. MacNaughton Richard J. A. Wilson Margaret M. Kelly Kathy D. McCoy Keith A. Sharkey Marie-Claire Arrieta
author_facet	Erik van Tilburg Bernardes Veronika Kuchařová Pettersen Mackenzie W. Gutierrez Isabelle Laforest-Lapointe Nicholas G. Jendzjowsky Jean-Baptiste Cavin Fernando A. Vicentini Catherine M. Keenan Hena R. Ramay Jumana Samara Wallace K. MacNaughton Richard J. A. Wilson Margaret M. Kelly Kathy D. McCoy Keith A. Sharkey Marie-Claire Arrieta
author_sort	Erik van Tilburg Bernardes
title	Intestinal fungi are causally implicated in microbiome assembly and immune development in mice
title_short	Intestinal fungi are causally implicated in microbiome assembly and immune development in mice
title_full	Intestinal fungi are causally implicated in microbiome assembly and immune development in mice
title_fullStr	Intestinal fungi are causally implicated in microbiome assembly and immune development in mice
title_full_unstemmed	Intestinal fungi are causally implicated in microbiome assembly and immune development in mice
title_sort	intestinal fungi are causally implicated in microbiome assembly and immune development in mice
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7e7a71db7d15468095e5d2a5ace43434
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Intestinal fungi are causally implicated in microbiome assembly and immune development in mice

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