Development of squaraine based G-quadruplex ligands using click chemistry

Development of squaraine based G-quadruplex ligands using click chemistry

Abstract The G-quadruplex (G4) structures of nucleic acids are considered to play an intrinsic role in gene expression. To this end, the development of new G4 ligands has attracted extensive research interests towards potential applications as G4-targeted drugs and molecular probes. To date, the maj...

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Autores principales: Xin Zhang, Yongbiao Wei, Tao Bing, Xiangjun Liu, Nan Zhang, Junyan Wang, Junqing He, Bing Jin, Dihua Shangguan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/7e85dac7107b4a2da4b7cc78844c3336
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