Development of squaraine based G-quadruplex ligands using click chemistry
Abstract The G-quadruplex (G4) structures of nucleic acids are considered to play an intrinsic role in gene expression. To this end, the development of new G4 ligands has attracted extensive research interests towards potential applications as G4-targeted drugs and molecular probes. To date, the maj...
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Main Authors: | Xin Zhang, Yongbiao Wei, Tao Bing, Xiangjun Liu, Nan Zhang, Junyan Wang, Junqing He, Bing Jin, Dihua Shangguan |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/7e85dac7107b4a2da4b7cc78844c3336 |
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