Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes.
Myelination is essential for rapid impulse conduction in the CNS, but what determines whether an individual axon becomes myelinated remains unknown. Here we show, using a myelinating coculture system, that there are two distinct modes of myelination, one that is independent of neuronal activity and...
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Autores principales: | Iben Lundgaard, Aryna Luzhynskaya, John H Stockley, Zhen Wang, Kimberley A Evans, Matthew Swire, Katrin Volbracht, Hélène O B Gautier, Robin J M Franklin, Charles Ffrench-Constant, David Attwell, Ragnhildur T Káradóttir |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/7e96a805c1684d3badfd87ae39c156c2 |
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