Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery
Despite their potential application as drug-delivery carriers, covalent organic frameworks (COF) have been only evaluated in vitro. Here the authors show by real time tracking in vivo the cell uptake of anticancer-drug loaded and water dispersible COFs.
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Nature Portfolio
2018
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oai:doaj.org-article:7e97ae72191145f3ba1181bea9c4409d2021-12-02T13:24:16ZWater-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery10.1038/s41467-018-04910-52041-1723https://doaj.org/article/7e97ae72191145f3ba1181bea9c4409d2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04910-5https://doaj.org/toc/2041-1723Despite their potential application as drug-delivery carriers, covalent organic frameworks (COF) have been only evaluated in vitro. Here the authors show by real time tracking in vivo the cell uptake of anticancer-drug loaded and water dispersible COFs.Guiyang ZhangXinle LiQiaobo LiaoYanfeng LiuKai XiWenyu HuangXudong JiaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Guiyang Zhang Xinle Li Qiaobo Liao Yanfeng Liu Kai Xi Wenyu Huang Xudong Jia Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery |
description |
Despite their potential application as drug-delivery carriers, covalent organic frameworks (COF) have been only evaluated in vitro. Here the authors show by real time tracking in vivo the cell uptake of anticancer-drug loaded and water dispersible COFs. |
format |
article |
author |
Guiyang Zhang Xinle Li Qiaobo Liao Yanfeng Liu Kai Xi Wenyu Huang Xudong Jia |
author_facet |
Guiyang Zhang Xinle Li Qiaobo Liao Yanfeng Liu Kai Xi Wenyu Huang Xudong Jia |
author_sort |
Guiyang Zhang |
title |
Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery |
title_short |
Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery |
title_full |
Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery |
title_fullStr |
Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery |
title_full_unstemmed |
Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery |
title_sort |
water-dispersible peg-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/7e97ae72191145f3ba1181bea9c4409d |
work_keys_str_mv |
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