Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery

Despite their potential application as drug-delivery carriers, covalent organic frameworks (COF) have been only evaluated in vitro. Here the authors show by real time tracking in vivo the cell uptake of anticancer-drug loaded and water dispersible COFs.

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Autores principales: Guiyang Zhang, Xinle Li, Qiaobo Liao, Yanfeng Liu, Kai Xi, Wenyu Huang, Xudong Jia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/7e97ae72191145f3ba1181bea9c4409d
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spelling oai:doaj.org-article:7e97ae72191145f3ba1181bea9c4409d2021-12-02T13:24:16ZWater-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery10.1038/s41467-018-04910-52041-1723https://doaj.org/article/7e97ae72191145f3ba1181bea9c4409d2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04910-5https://doaj.org/toc/2041-1723Despite their potential application as drug-delivery carriers, covalent organic frameworks (COF) have been only evaluated in vitro. Here the authors show by real time tracking in vivo the cell uptake of anticancer-drug loaded and water dispersible COFs.Guiyang ZhangXinle LiQiaobo LiaoYanfeng LiuKai XiWenyu HuangXudong JiaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Guiyang Zhang
Xinle Li
Qiaobo Liao
Yanfeng Liu
Kai Xi
Wenyu Huang
Xudong Jia
Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery
description Despite their potential application as drug-delivery carriers, covalent organic frameworks (COF) have been only evaluated in vitro. Here the authors show by real time tracking in vivo the cell uptake of anticancer-drug loaded and water dispersible COFs.
format article
author Guiyang Zhang
Xinle Li
Qiaobo Liao
Yanfeng Liu
Kai Xi
Wenyu Huang
Xudong Jia
author_facet Guiyang Zhang
Xinle Li
Qiaobo Liao
Yanfeng Liu
Kai Xi
Wenyu Huang
Xudong Jia
author_sort Guiyang Zhang
title Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery
title_short Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery
title_full Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery
title_fullStr Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery
title_full_unstemmed Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery
title_sort water-dispersible peg-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/7e97ae72191145f3ba1181bea9c4409d
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