Simultaneous topography-guided PRK followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus

Leopoldo Spadea,1 Marino Paroli21University of L&rsquo;Aquila, Department of Biotechnological and Applied Clinical Sciences, Eye Clinic, L&rsquo;Aquila, 2La Sapienza University, Department of Biotechnology and Medical-Surgical Sciences, Latina, ItalyBackground: The purpose of this pa...

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Autores principales:	Spadea L, Paroli M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/7e9dda22b60a4ede9dc9e4f04997d8b2
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spelling	oai:doaj.org-article:7e9dda22b60a4ede9dc9e4f04997d8b22021-12-02T04:48:52ZSimultaneous topography-guided PRK followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus1177-54671177-5483https://doaj.org/article/7e9dda22b60a4ede9dc9e4f04997d8b22012-11-01T00:00:00Zhttp://www.dovepress.com/simultaneous-topography-guided-prk-followed-by-corneal-collagen-cross--a11432https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Leopoldo Spadea,1 Marino Paroli21University of L&rsquo;Aquila, Department of Biotechnological and Applied Clinical Sciences, Eye Clinic, L&rsquo;Aquila, 2La Sapienza University, Department of Biotechnology and Medical-Surgical Sciences, Latina, ItalyBackground: The purpose of this paper is to report the results of using combined treatment of customized excimer laser-assisted photorefractive keratectomy (PRK) and prophylactic corneal collagen crosslinking (CXL) for residual refractive error in a group of patients who had previously undergone lamellar keratoplasty for keratoconus.Methods: The study included 14 eyes from 14 patients who had originally been treated for keratoconus in one eye by excimer laser-assisted lamellar keratoplasty (ELLK), and subsequently presented with residual ametropia (-6.11 D &plusmn; 2.48, range -2.50 to -9.50). After a mean 40.1 &plusmn; 12.4 months since ELLK they underwent combined simultaneous corneal regularization treatment with topographically guided transepithelial excimer laser PRK (central corneal regularization) and corneal CXL induced by riboflavin-ultraviolet A.Results: After a mean 15 &plusmn; 6.5 (range 6&ndash;24) months, all eyes gained at least one Snellen line of uncorrected distance visual acuity (range 1&ndash;10). No patient lost lines of corrected distance visual acuity, and four patients gained three lines of corrected distance visual acuity. Mean manifest refractive spherical equivalent was -0.79 &plusmn; 2.09 (range +1 to -3.0) D, and topographic keratometric astigmatism was 5.02 &plusmn; 2.93 (range 0.8&ndash;8.9) D. All the corneas remained clear (haze&nbsp;&lt; 1).Conclusion: The combination of customized PRK and corneal CXL provided safe and effective results in the management of corneal regularization for refractive purposes after ELLK for keratoconus.Keywords: corneal collagen crosslinking, excimer laser-assisted lamellar keratoplasty, photorefractive keratectomySpadea LParoli MDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 1793-1800 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Spadea L Paroli M Simultaneous topography-guided PRK followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus
description	Leopoldo Spadea,1 Marino Paroli21University of L&rsquo;Aquila, Department of Biotechnological and Applied Clinical Sciences, Eye Clinic, L&rsquo;Aquila, 2La Sapienza University, Department of Biotechnology and Medical-Surgical Sciences, Latina, ItalyBackground: The purpose of this paper is to report the results of using combined treatment of customized excimer laser-assisted photorefractive keratectomy (PRK) and prophylactic corneal collagen crosslinking (CXL) for residual refractive error in a group of patients who had previously undergone lamellar keratoplasty for keratoconus.Methods: The study included 14 eyes from 14 patients who had originally been treated for keratoconus in one eye by excimer laser-assisted lamellar keratoplasty (ELLK), and subsequently presented with residual ametropia (-6.11 D &plusmn; 2.48, range -2.50 to -9.50). After a mean 40.1 &plusmn; 12.4 months since ELLK they underwent combined simultaneous corneal regularization treatment with topographically guided transepithelial excimer laser PRK (central corneal regularization) and corneal CXL induced by riboflavin-ultraviolet A.Results: After a mean 15 &plusmn; 6.5 (range 6&ndash;24) months, all eyes gained at least one Snellen line of uncorrected distance visual acuity (range 1&ndash;10). No patient lost lines of corrected distance visual acuity, and four patients gained three lines of corrected distance visual acuity. Mean manifest refractive spherical equivalent was -0.79 &plusmn; 2.09 (range +1 to -3.0) D, and topographic keratometric astigmatism was 5.02 &plusmn; 2.93 (range 0.8&ndash;8.9) D. All the corneas remained clear (haze&nbsp;&lt; 1).Conclusion: The combination of customized PRK and corneal CXL provided safe and effective results in the management of corneal regularization for refractive purposes after ELLK for keratoconus.Keywords: corneal collagen crosslinking, excimer laser-assisted lamellar keratoplasty, photorefractive keratectomy
format	article
author	Spadea L Paroli M
author_facet	Spadea L Paroli M
author_sort	Spadea L
title	Simultaneous topography-guided PRK followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus
title_short	Simultaneous topography-guided PRK followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus
title_full	Simultaneous topography-guided PRK followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus
title_fullStr	Simultaneous topography-guided PRK followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus
title_full_unstemmed	Simultaneous topography-guided PRK followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus
title_sort	simultaneous topography-guided prk followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/7e9dda22b60a4ede9dc9e4f04997d8b2
work_keys_str_mv	AT spadeal simultaneoustopographyguidedprkfollowedbycornealcollagencrosslinkingafterlamellarkeratoplastyforkeratoconus AT parolim simultaneoustopographyguidedprkfollowedbycornealcollagencrosslinkingafterlamellarkeratoplastyforkeratoconus
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Simultaneous topography-guided PRK followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus

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