Novel Nonreplicating Vaccinia Virus Vector Enhances Expression of Heterologous Genes and Suppresses Synthesis of Endogenous Viral Proteins
ABSTRACT Viruses are used as expression vectors for protein synthesis, immunology research, vaccines, and therapeutics. Advantages of poxvirus vectors include the accommodation of large amounts of heterologous DNA, the presence of a cytoplasmic site of transcription, and high expression levels. On t...
Guardado en:
Autores principales: | Linda S. Wyatt, Wei Xiao, Jeffrey L. Americo, Patricia L. Earl, Bernard Moss |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7e9fa5a04ee54f58a95c61819c4b3e6d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Assessment of an LSDV-Vectored Vaccine for Heterologous Prime-Boost Immunizations against HIV
por: Ros Chapman, et al.
Publicado: (2021) -
Influenza Virus Polymerase Mutation Stabilizes a Foreign Gene Inserted into the Virus Genome by Enhancing the Transcription/Replication Efficiency of the Modified Segment
por: Yuri Furusawa, et al.
Publicado: (2019) -
Ancient Gene Capture and Recent Gene Loss Shape the Evolution of Orthopoxvirus-Host Interaction Genes
por: Tatiana G. Senkevich, et al.
Publicado: (2021) -
Heterosubtypic Protection Induced by a Live Attenuated Influenza Virus Vaccine Expressing Galactose-α-1,3-Galactose Epitopes in Infected Cells
por: Li-Meng Yan, et al.
Publicado: (2020) -
Epistatic Interactions within the Influenza A Virus Polymerase Complex Mediate Mutagen Resistance and Replication Fidelity
por: Matthew D. Pauly, et al.
Publicado: (2017)