Novel Nonreplicating Vaccinia Virus Vector Enhances Expression of Heterologous Genes and Suppresses Synthesis of Endogenous Viral Proteins

ABSTRACT Viruses are used as expression vectors for protein synthesis, immunology research, vaccines, and therapeutics. Advantages of poxvirus vectors include the accommodation of large amounts of heterologous DNA, the presence of a cytoplasmic site of transcription, and high expression levels. On t...

Full description

Saved in:
Bibliographic Details
Main Authors: Linda S. Wyatt, Wei Xiao, Jeffrey L. Americo, Patricia L. Earl, Bernard Moss
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
Online Access:https://doaj.org/article/7e9fa5a04ee54f58a95c61819c4b3e6d
Tags: Add Tag
No Tags, Be the first to tag this record!