Item-level analyses reveal genetic heterogeneity in neuroticism

Neuroticism can be assessed as a composite score of individual items. Here, Nagel et al. perform genetic association studies for 12 neuroticism items and the sum-score and demonstrate genetic heterogeneity at the item-level.

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Autores principales: Mats Nagel, Kyoko Watanabe, Sven Stringer, Danielle Posthuma, Sophie van der Sluis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/7e9fd55c065d4717ac52709cbb4a6ab9
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spelling oai:doaj.org-article:7e9fd55c065d4717ac52709cbb4a6ab92021-12-02T16:56:44ZItem-level analyses reveal genetic heterogeneity in neuroticism10.1038/s41467-018-03242-82041-1723https://doaj.org/article/7e9fd55c065d4717ac52709cbb4a6ab92018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03242-8https://doaj.org/toc/2041-1723Neuroticism can be assessed as a composite score of individual items. Here, Nagel et al. perform genetic association studies for 12 neuroticism items and the sum-score and demonstrate genetic heterogeneity at the item-level.Mats NagelKyoko WatanabeSven StringerDanielle PosthumaSophie van der SluisNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mats Nagel
Kyoko Watanabe
Sven Stringer
Danielle Posthuma
Sophie van der Sluis
Item-level analyses reveal genetic heterogeneity in neuroticism
description Neuroticism can be assessed as a composite score of individual items. Here, Nagel et al. perform genetic association studies for 12 neuroticism items and the sum-score and demonstrate genetic heterogeneity at the item-level.
format article
author Mats Nagel
Kyoko Watanabe
Sven Stringer
Danielle Posthuma
Sophie van der Sluis
author_facet Mats Nagel
Kyoko Watanabe
Sven Stringer
Danielle Posthuma
Sophie van der Sluis
author_sort Mats Nagel
title Item-level analyses reveal genetic heterogeneity in neuroticism
title_short Item-level analyses reveal genetic heterogeneity in neuroticism
title_full Item-level analyses reveal genetic heterogeneity in neuroticism
title_fullStr Item-level analyses reveal genetic heterogeneity in neuroticism
title_full_unstemmed Item-level analyses reveal genetic heterogeneity in neuroticism
title_sort item-level analyses reveal genetic heterogeneity in neuroticism
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/7e9fd55c065d4717ac52709cbb4a6ab9
work_keys_str_mv AT matsnagel itemlevelanalysesrevealgeneticheterogeneityinneuroticism
AT kyokowatanabe itemlevelanalysesrevealgeneticheterogeneityinneuroticism
AT svenstringer itemlevelanalysesrevealgeneticheterogeneityinneuroticism
AT danielleposthuma itemlevelanalysesrevealgeneticheterogeneityinneuroticism
AT sophievandersluis itemlevelanalysesrevealgeneticheterogeneityinneuroticism
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