Brain pathology recapitulates physiology: A network meta-analysis
Peter Fox & Thomas Vanasse et al. compare atrophy patterns in 40+ brain disorders with healthy task-activation networks across 100+ behavioral domains. Their analyses demonstrate strong spatial correspondence between disease-related structural coalterations and functional networks, an observatio...
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| Autores principales: | , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/7ea39088289945e18068c80e6d518c40 |
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| Sumario: | Peter Fox & Thomas Vanasse et al. compare atrophy patterns in 40+ brain disorders with healthy task-activation networks across 100+ behavioral domains. Their analyses demonstrate strong spatial correspondence between disease-related structural coalterations and functional networks, an observation that greatly extends the scope of the network-degeneration hypothesis. Further, the metabolic cost of network hubs (nodal stress) is implicated as a common mechanism across a wide range of brain disorders. |
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