Brain pathology recapitulates physiology: A network meta-analysis

Peter Fox & Thomas Vanasse et al. compare atrophy patterns in 40+ brain disorders with healthy task-activation networks across 100+ behavioral domains. Their analyses demonstrate strong spatial correspondence between disease-related structural coalterations and functional networks, an observatio...

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Autores principales:	Thomas J. Vanasse, Peter T. Fox, P. Mickle Fox, Franco Cauda, Tommaso Costa, Stephen M. Smith, Simon B. Eickhoff, Jack L. Lancaster
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/7ea39088289945e18068c80e6d518c40
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spelling	oai:doaj.org-article:7ea39088289945e18068c80e6d518c402021-12-02T13:19:28ZBrain pathology recapitulates physiology: A network meta-analysis10.1038/s42003-021-01832-92399-3642https://doaj.org/article/7ea39088289945e18068c80e6d518c402021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01832-9https://doaj.org/toc/2399-3642Peter Fox & Thomas Vanasse et al. compare atrophy patterns in 40+ brain disorders with healthy task-activation networks across 100+ behavioral domains. Their analyses demonstrate strong spatial correspondence between disease-related structural coalterations and functional networks, an observation that greatly extends the scope of the network-degeneration hypothesis. Further, the metabolic cost of network hubs (nodal stress) is implicated as a common mechanism across a wide range of brain disorders.Thomas J. VanassePeter T. FoxP. Mickle FoxFranco CaudaTommaso CostaStephen M. SmithSimon B. EickhoffJack L. LancasterNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Thomas J. Vanasse Peter T. Fox P. Mickle Fox Franco Cauda Tommaso Costa Stephen M. Smith Simon B. Eickhoff Jack L. Lancaster Brain pathology recapitulates physiology: A network meta-analysis
description	Peter Fox & Thomas Vanasse et al. compare atrophy patterns in 40+ brain disorders with healthy task-activation networks across 100+ behavioral domains. Their analyses demonstrate strong spatial correspondence between disease-related structural coalterations and functional networks, an observation that greatly extends the scope of the network-degeneration hypothesis. Further, the metabolic cost of network hubs (nodal stress) is implicated as a common mechanism across a wide range of brain disorders.
format	article
author	Thomas J. Vanasse Peter T. Fox P. Mickle Fox Franco Cauda Tommaso Costa Stephen M. Smith Simon B. Eickhoff Jack L. Lancaster
author_facet	Thomas J. Vanasse Peter T. Fox P. Mickle Fox Franco Cauda Tommaso Costa Stephen M. Smith Simon B. Eickhoff Jack L. Lancaster
author_sort	Thomas J. Vanasse
title	Brain pathology recapitulates physiology: A network meta-analysis
title_short	Brain pathology recapitulates physiology: A network meta-analysis
title_full	Brain pathology recapitulates physiology: A network meta-analysis
title_fullStr	Brain pathology recapitulates physiology: A network meta-analysis
title_full_unstemmed	Brain pathology recapitulates physiology: A network meta-analysis
title_sort	brain pathology recapitulates physiology: a network meta-analysis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7ea39088289945e18068c80e6d518c40
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Brain pathology recapitulates physiology: A network meta-analysis

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