A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis
While hundreds of loci are linked with inflammatory bowel diseases (IBDs), the functional consequences of the associated variants remain unclear. Here, the authors screened in ulcerative colitis (UC) patients’ genomes for protein-truncating variants near IBD loci, and identify a protein truncating v...
Guardado en:
Ejemplares similares
-
Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis
por: Manuel A. Rivas, et al.
Publicado: (2016) -
A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis
por: International Multiple Sclerosis Genetics Consortium
Publicado: (2019) -
Author Correction: A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis
por: International Multiple Sclerosis Genetics Consortium
Publicado: (2019) -
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease
por: N. T. Ventham, et al.
Publicado: (2016) -
Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease
por: Eva Gonçalves Serra, et al.
Publicado: (2020)