The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly

Danny Ulahannan, Adrian WaggDepartment of Geriatric Medicine, University College Hospital, London, UKAbstract: After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affec...

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Autores principales: Danny Ulahannan, Adrian Wagg
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Lenguaje:EN
Publicado: Dove Medical Press 2009
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Acceso en línea:https://doaj.org/article/7ecdbb11e6b34920961bfaa4c66f2845
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spelling oai:doaj.org-article:7ecdbb11e6b34920961bfaa4c66f28452021-12-02T04:07:46ZThe safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly1178-1998https://doaj.org/article/7ecdbb11e6b34920961bfaa4c66f28452009-04-01T00:00:00Zhttps://www.dovepress.com/the-safety-and-efficacy-of-tolterodine-extended-release-in-the-treatme-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Danny Ulahannan, Adrian WaggDepartment of Geriatric Medicine, University College Hospital, London, UKAbstract: After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affects older people, who experience the most severe disease, and are also at a greater risk of side effects from antimuscarinic therapy. Thus it is imperative that data are available on the efficacy and tolerability of this group of drugs when used in older people. This article reviews the pathophysiology of the condition, its effect on the elderly and the evidence for the use of extended release tolterodine in the elderly using data from placebo and active drug controlled studies.Keywords: overactive bladder, tolterodine, urgency incontinenceDanny UlahannanAdrian WaggDove Medical Pressarticleoveractive bladdertolterodineurgency incontinenceGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 4, Pp 191-196 (2009)
institution DOAJ
collection DOAJ
language EN
topic overactive bladder
tolterodine
urgency incontinence
Geriatrics
RC952-954.6
spellingShingle overactive bladder
tolterodine
urgency incontinence
Geriatrics
RC952-954.6
Danny Ulahannan
Adrian Wagg
The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
description Danny Ulahannan, Adrian WaggDepartment of Geriatric Medicine, University College Hospital, London, UKAbstract: After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affects older people, who experience the most severe disease, and are also at a greater risk of side effects from antimuscarinic therapy. Thus it is imperative that data are available on the efficacy and tolerability of this group of drugs when used in older people. This article reviews the pathophysiology of the condition, its effect on the elderly and the evidence for the use of extended release tolterodine in the elderly using data from placebo and active drug controlled studies.Keywords: overactive bladder, tolterodine, urgency incontinence
format article
author Danny Ulahannan
Adrian Wagg
author_facet Danny Ulahannan
Adrian Wagg
author_sort Danny Ulahannan
title The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
title_short The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
title_full The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
title_fullStr The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
title_full_unstemmed The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
title_sort safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
publisher Dove Medical Press
publishDate 2009
url https://doaj.org/article/7ecdbb11e6b34920961bfaa4c66f2845
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