Intratracheal inoculation of AHc vaccine induces protection against aerosolized botulinum neurotoxin A challenge in mice

Abstract Botulinum neurotoxin (BoNT), produced by Clostridium botulinum, is generally known to be the most poisonous of all biological toxins. In this study, we evaluate the protection conferred by intratracheal (i.t.) inoculation immunization with recombinant Hc subunit (AHc) vaccines against aeros...

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Autores principales: Changjiao Gan, Wenbo Luo, Yunzhou Yu, Zhouguang Jiao, Sha Li, Duo Su, Junxia Feng, Xiaodong Zhao, Yefeng Qiu, Lingfei Hu, Dongsheng Zhou, Xiaolu Xiong, Jinglin Wang, Huiying Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7ecfa95b4a8e41dfbba20ce2f3724ce7
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