CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion
During cell division, centrosomes duplicate and newly formed centrioles must undergo centriole-to-centrosome conversion, but the molecular details are unclear. Here, the authors report that the centriole microtubule-triplet 9-fold structure scaffolds pericentriolar proteins and permits the conversio...
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2020
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oai:doaj.org-article:7edd0d04019540369cf2793ec4ea00252021-12-02T15:37:12ZCEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion10.1038/s41467-020-14767-22041-1723https://doaj.org/article/7edd0d04019540369cf2793ec4ea00252020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14767-2https://doaj.org/toc/2041-1723During cell division, centrosomes duplicate and newly formed centrioles must undergo centriole-to-centrosome conversion, but the molecular details are unclear. Here, the authors report that the centriole microtubule-triplet 9-fold structure scaffolds pericentriolar proteins and permits the conversion of centrioles to fully functional centrosomes.Enrico S. AtorinoShoji HataCharlotta FunayaAnnett NeunerElmar SchiebelNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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Science Q Enrico S. Atorino Shoji Hata Charlotta Funaya Annett Neuner Elmar Schiebel CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion |
description |
During cell division, centrosomes duplicate and newly formed centrioles must undergo centriole-to-centrosome conversion, but the molecular details are unclear. Here, the authors report that the centriole microtubule-triplet 9-fold structure scaffolds pericentriolar proteins and permits the conversion of centrioles to fully functional centrosomes. |
format |
article |
author |
Enrico S. Atorino Shoji Hata Charlotta Funaya Annett Neuner Elmar Schiebel |
author_facet |
Enrico S. Atorino Shoji Hata Charlotta Funaya Annett Neuner Elmar Schiebel |
author_sort |
Enrico S. Atorino |
title |
CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion |
title_short |
CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion |
title_full |
CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion |
title_fullStr |
CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion |
title_full_unstemmed |
CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion |
title_sort |
cep44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/7edd0d04019540369cf2793ec4ea0025 |
work_keys_str_mv |
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