ImmGen report: sexual dimorphism in the immune system transcriptome

Sexual dimorphism is observed frequently in immune disorders, but the underlying insights are still unclear. Here the authors analyze transcriptome and epigenome changes induced by interferon in various mouse immune cell types, and find only a restricted set of sexual dimorphism genes in innate immu...

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Autores principales: Shani Talia Gal-Oz, Barbara Maier, Hideyuki Yoshida, Kumba Seddu, Nitzan Elbaz, Charles Czysz, Or Zuk, Barbara E. Stranger, Hadas Ner-Gaon, Tal Shay
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/7edf4141b4694c18b29bc046370500ac
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spelling oai:doaj.org-article:7edf4141b4694c18b29bc046370500ac2021-12-02T17:01:59ZImmGen report: sexual dimorphism in the immune system transcriptome10.1038/s41467-019-12348-62041-1723https://doaj.org/article/7edf4141b4694c18b29bc046370500ac2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12348-6https://doaj.org/toc/2041-1723Sexual dimorphism is observed frequently in immune disorders, but the underlying insights are still unclear. Here the authors analyze transcriptome and epigenome changes induced by interferon in various mouse immune cell types, and find only a restricted set of sexual dimorphism genes in innate immunity and macrophages.Shani Talia Gal-OzBarbara MaierHideyuki YoshidaKumba SedduNitzan ElbazCharles CzyszOr ZukBarbara E. StrangerHadas Ner-GaonTal ShayNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shani Talia Gal-Oz
Barbara Maier
Hideyuki Yoshida
Kumba Seddu
Nitzan Elbaz
Charles Czysz
Or Zuk
Barbara E. Stranger
Hadas Ner-Gaon
Tal Shay
ImmGen report: sexual dimorphism in the immune system transcriptome
description Sexual dimorphism is observed frequently in immune disorders, but the underlying insights are still unclear. Here the authors analyze transcriptome and epigenome changes induced by interferon in various mouse immune cell types, and find only a restricted set of sexual dimorphism genes in innate immunity and macrophages.
format article
author Shani Talia Gal-Oz
Barbara Maier
Hideyuki Yoshida
Kumba Seddu
Nitzan Elbaz
Charles Czysz
Or Zuk
Barbara E. Stranger
Hadas Ner-Gaon
Tal Shay
author_facet Shani Talia Gal-Oz
Barbara Maier
Hideyuki Yoshida
Kumba Seddu
Nitzan Elbaz
Charles Czysz
Or Zuk
Barbara E. Stranger
Hadas Ner-Gaon
Tal Shay
author_sort Shani Talia Gal-Oz
title ImmGen report: sexual dimorphism in the immune system transcriptome
title_short ImmGen report: sexual dimorphism in the immune system transcriptome
title_full ImmGen report: sexual dimorphism in the immune system transcriptome
title_fullStr ImmGen report: sexual dimorphism in the immune system transcriptome
title_full_unstemmed ImmGen report: sexual dimorphism in the immune system transcriptome
title_sort immgen report: sexual dimorphism in the immune system transcriptome
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/7edf4141b4694c18b29bc046370500ac
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