ImmGen report: sexual dimorphism in the immune system transcriptome
Sexual dimorphism is observed frequently in immune disorders, but the underlying insights are still unclear. Here the authors analyze transcriptome and epigenome changes induced by interferon in various mouse immune cell types, and find only a restricted set of sexual dimorphism genes in innate immu...
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Nature Portfolio
2019
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oai:doaj.org-article:7edf4141b4694c18b29bc046370500ac2021-12-02T17:01:59ZImmGen report: sexual dimorphism in the immune system transcriptome10.1038/s41467-019-12348-62041-1723https://doaj.org/article/7edf4141b4694c18b29bc046370500ac2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12348-6https://doaj.org/toc/2041-1723Sexual dimorphism is observed frequently in immune disorders, but the underlying insights are still unclear. Here the authors analyze transcriptome and epigenome changes induced by interferon in various mouse immune cell types, and find only a restricted set of sexual dimorphism genes in innate immunity and macrophages.Shani Talia Gal-OzBarbara MaierHideyuki YoshidaKumba SedduNitzan ElbazCharles CzyszOr ZukBarbara E. StrangerHadas Ner-GaonTal ShayNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
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Science Q Shani Talia Gal-Oz Barbara Maier Hideyuki Yoshida Kumba Seddu Nitzan Elbaz Charles Czysz Or Zuk Barbara E. Stranger Hadas Ner-Gaon Tal Shay ImmGen report: sexual dimorphism in the immune system transcriptome |
description |
Sexual dimorphism is observed frequently in immune disorders, but the underlying insights are still unclear. Here the authors analyze transcriptome and epigenome changes induced by interferon in various mouse immune cell types, and find only a restricted set of sexual dimorphism genes in innate immunity and macrophages. |
format |
article |
author |
Shani Talia Gal-Oz Barbara Maier Hideyuki Yoshida Kumba Seddu Nitzan Elbaz Charles Czysz Or Zuk Barbara E. Stranger Hadas Ner-Gaon Tal Shay |
author_facet |
Shani Talia Gal-Oz Barbara Maier Hideyuki Yoshida Kumba Seddu Nitzan Elbaz Charles Czysz Or Zuk Barbara E. Stranger Hadas Ner-Gaon Tal Shay |
author_sort |
Shani Talia Gal-Oz |
title |
ImmGen report: sexual dimorphism in the immune system transcriptome |
title_short |
ImmGen report: sexual dimorphism in the immune system transcriptome |
title_full |
ImmGen report: sexual dimorphism in the immune system transcriptome |
title_fullStr |
ImmGen report: sexual dimorphism in the immune system transcriptome |
title_full_unstemmed |
ImmGen report: sexual dimorphism in the immune system transcriptome |
title_sort |
immgen report: sexual dimorphism in the immune system transcriptome |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/7edf4141b4694c18b29bc046370500ac |
work_keys_str_mv |
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