The COMET toolkit for composing customizable genetic programs in mammalian cells

Engineering mammalian cellular functions requires a toolkit of orthogonal and well-characterized genetic components. Here the authors develop COMET: an ensemble of transcription factors, promoters, and accompanying models for the design and construction of genetic programs.

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Bibliographic Details
Main Authors: Patrick S. Donahue, Joseph W. Draut, Joseph J. Muldoon, Hailey I. Edelstein, Neda Bagheri, Joshua N. Leonard
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Q
Online Access:https://doaj.org/article/7ee29a59a9554e1ba69e92cbf22088a7
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